Protein Alignment zen2 and nkx2.2a

DIOPT Version :10

• Sequence 1: NP_476794.1
• Gene: zen2 / 40827
• FlyBaseID: FBgn0004054
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_571497.2
• Gene: nkx2.2a / 30697
• ZFINID: ZDB-GENE-980526-403
• Length: 273
• Species: Danio rerio
• Alignment Length: 216
• Identity: 54/216 - (25%)
• Similarity: 82/216 - (37%)
• Gaps: 68/216 - (31%)

  Fly     7 ENYFVDN--------YSVSDLMMYPCVELNVEAAPTAT----------------TRS----SEKS 43
            :|.|.||        .:.:|.:.|....|:..:..|:.                |.|    |.|.
Zfish    65 KNPFYDNSDNPYTRWLATTDSIQYSLHGLSANSQDTSAKSPEPSADESPDNDKETSSNGSDSGKK 129

  Fly    44 KRSRTAFSSLQLIELEREFHLNKYLARTRRIEISQRLALTERQVKIWFQNRRMKLKKSTNRKG-- 106
            ::.|..||..|..||||.|...:||:...|..::..:.||..||||||||.|.|:|::...||
Zfish   130 RKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGME 194

  Fly   107 ----------AIGALT-------------------TSIPLSSQSSEDLQKDDQIVERLLRY-ANT 141
                      |:..|.                   ..||.|:.|::.||.        ::| |:.
Zfish   195 VTHLPSPRRVAVPVLVRDGKPCHTLKAQDLAATFQAGIPFSAYSAQSLQH--------MQYNAHY 251

  Fly   142 NVETAPLRQVDHGVLEEGQIT 162
            :..|.|.....|.:::..|.|
Zfish   252 SAATTPQFPTAHHLVQTQQWT 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen2	NP_476794.1	Homeodomain	44..100	CDD:459649	24/55 (44%)
nkx2.2a	NP_571497.2	COG5576	93..218	CDD:227863	35/124 (28%)
		Homeodomain	130..186	CDD:459649	24/55 (44%)