DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment zen2 and GSX2

DIOPT Version :9

Sequence 1:	NP_476794.1	Gene:	zen2 / 40827	FlyBaseID:	FBgn0004054	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_573574.2	Gene:	GSX2 / 170825	HGNCID:	24959	Length:	304	Species:	Homo sapiens

Alignment Length:	138	Identity:	57/138 - (41%)
Similarity:	74/138 - (53%)	Gaps:	14/138 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YSVSDLMMYPCVELNVEAAPTATTRSSEKSKRSRTAFSSLQLIELEREFHLNKYLARTRRIEISQ 78
            |:|:|...:.|:.:....|...     ...||.||||:|.||:||||||..|.||:|.|||||:.
Human   178 YNVADPRRFHCLTMGGSDASQV-----PNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIAT 237

  Fly    79 RLALTERQVKIWFQNRRMKLK---KSTNRKGAIGALTTSIPLSSQSSEDLQKDDQIVERLLRYAN 140
            .|.|:|:||||||||||:|.|   |.|.|....|.......:....|||   :|.:..   ..||
Human   238 YLNLSEKQVKIWFQNRRVKHKKEGKGTQRNSHAGCKCVGSQVHYARSED---EDSLSP---ASAN 296

  Fly   141 TNVETAPL 148
            .:.|.:||
Human   297 DDKEISPL 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zen2	NP_476794.1	Homeobox	46..99	CDD:278475	36/52 (69%)
GSX2	NP_573574.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..151
		Homeobox	206..258	CDD:306543	36/51 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	283..304		7/26 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155071
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740