Protein Alignment zen2 and Hoxd3

DIOPT Version :10

• Sequence 1: NP_476794.1
• Gene: zen2 / 40827
• FlyBaseID: FBgn0004054
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_034598.2
• Gene: Hoxd3 / 15434
• MGIID: 96207
• Length: 433
• Species: Mus musculus
• Alignment Length: 234
• Identity: 78/234 - (33%)
• Similarity: 103/234 - (44%)
• Gaps: 71/234 - (30%)

  Fly    43 SKRSRTAFSSLQLIELEREFHLNKYLARTRRIEISQRLALTERQVKIWFQNRRMKLKKSTNRKGA 107
            |||.|||::|.||:|||:|||.|:||.|.||:|::..|.|||||:||||||||||.||....||.
Mouse   195 SKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGI 259

  Fly   108 IGALTTSIPLSSQSSEDLQKDDQIVERLLRYANTNVETAPLRQVDHGVLEEGQITP-PYQSYDYL 171
            :.:     | :.||.|                    .:.||......|...||:.| |..:||
Mouse   260 LHS-----P-AGQSPE--------------------RSPPLGGAAGHVAYSGQLPPVPGLAYD-- 296

  Fly   172 HEFSPEPMA---------------------LPQ---LPFNEFD--------ANWASSWLGLEPTI 204
               :|.|.|                     |||   .|..||:        ..:||:.|...| :
Mouse   297 ---APSPPAFAKSQPNMYGLAAYTAPLSSCLPQQKRYPAPEFEPHPMASNGGGFASANLQGSP-V 357

  Fly   205 PIAENVIEHNTQDQPMIQNFCWDSNSSSASSSDILDVDY 243
            .:..|.::........:.|....|:.||||      |||
Mouse   358 YVGGNFVDSMAPTSGPVFNLGHLSHPSSAS------VDY 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen2	NP_476794.1	Homeodomain	44..100	CDD:459649	37/55 (67%)
Hoxd3	NP_034598.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..198		2/2 (100%)
		Antp-type hexapeptide	161..166
		Homeodomain	196..252	CDD:459649	37/55 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	258..280		7/47 (15%)
		DUF4074	370..431	CDD:463833	9/27 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	401..433