DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zen2 and Hoxc4

DIOPT Version :9

Sequence 1:	NP_476794.1	Gene:	zen2 / 40827	FlyBaseID:	FBgn0004054	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_038581.2	Gene:	Hoxc4 / 15423	MGIID:	96195	Length:	264	Species:	Mus musculus

Alignment Length:	157	Identity:	54/157 - (34%)
Similarity:	73/157 - (46%)	Gaps:	45/157 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 MMYPCVELNVEAAPTATTRSSEKSKRSRTAFSSLQLIELEREFHLNKYLARTRRIEISQRLALTE 84
            ::||.:: .:..:......:..:.||||||::..|::|||:|||.|:||.|.|||||:..|.|:|
Mouse   134 IVYPWMK-KIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSE 197

  Fly    85 RQVKIWFQNRRMKLKKSTNRKGAIGALTTSIPLSSQSSEDLQKDDQIVERLLRYANTNVETAP-- 147
            ||:||||||||||.||..                                  |..||.|.:||
Mouse   198 RQIKIWFQNRRMKWKKDH----------------------------------RLPNTKVRSAPPA 228

  Fly   148 ------LRQVDHGVLEE--GQITPPYQ 166
                  |.....|..|:  ...|||.|
Mouse   229 GAAPSTLSAATPGTSEDHSQSATPPEQ 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zen2	NP_476794.1	Homeobox	46..99	CDD:278475	35/52 (67%)
Hoxc4	NP_038581.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	19..130
		Antp-type hexapeptide	135..140		2/4 (50%)
		Homeobox	159..213	CDD:365835	35/53 (66%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	214..264		13/76 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810