DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zen2 and hoxd3

DIOPT Version :9

Sequence 1:	NP_476794.1	Gene:	zen2 / 40827	FlyBaseID:	FBgn0004054	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	XP_002935734.1	Gene:	hoxd3 / 100038058	XenbaseID:	XB-GENE-478462	Length:	415	Species:	Xenopus tropicalis

Alignment Length:	229	Identity:	77/229 - (33%)
Similarity:	105/229 - (45%)	Gaps:	43/229 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 EAAPTATTRSSEKSKRSRTAFSSLQLIELEREFHLNKYLARTRRIEISQRLALTERQVKIWFQNR 94
            |.:||..:     |||.|||::|.||:|||:|||.|:||.|.||:|::..|.|||||:|||||||
Frog   172 EKSPTGPS-----SKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNR 231

  Fly    95 RMKLKKSTNRKGAIGALTTSIP-----LSSQSSEDLQKDDQIVERLLRYANTNVETAPLRQVDHG 154
            |||.||....||.:.:.....|     ||..:..........|..|...|.:....|..:|..:|
Frog   232 RMKYKKDQKAKGIMHSPAGQSPDRSPTLSGSNHVGYSSQLPTVNSLSYDAPSPTSFAKSQQNMYG 296

  Fly   155 VLEEGQITPPYQSYDYLHEFSPEPMALPQ---LPFNEFD-------ANWASSWLGLEPTIPIAEN 209
            :   ...|.|..|            .|||   .|..|::       :.:|:..|...| :.:..|
Frog   297 L---AAYTAPLSS------------CLPQQKRYPGAEYEHHTMQGNSGFANPNLQGSP-VYVGGN 345

  Fly   210 VIEHNTQDQPMIQNFCWDSNSSSASSSDILDVDY 243
            .::......||. |....|:.||||      |||
Frog   346 FVDSMPASGPMF-NVGHLSHPSSAS------VDY 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zen2	NP_476794.1	Homeobox	46..99	CDD:278475	35/52 (67%)
hoxd3	XP_002935734.1	Homeobox	184..237	CDD:365835	35/52 (67%)
hoxd3	XP_002935734.1	DUF4074	352..413	CDD:372548	11/28 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910