Protein Alignment pb and ISX

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001290437.1
• Gene: ISX / 91464
• HGNCID: 28084
• Length: 245
• Species: Homo sapiens
• Alignment Length: 141
• Identity: 41/141 - (29%)
• Similarity: 56/141 - (39%)
• Gaps: 49/141 - (34%)

  Fly   116 PESPKIGTPVGSGAIGGVGVNVNVNVGVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNN 180
            ||.|....| |..|..|.|:                            |.|...:.:..|||.
Human    49 PEGPGEEGP-GEAAASGSGL----------------------------EKPPKDQPQEGRKSK-- 82

  Fly   181 NNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVW 245
                              ||:||.:|..||.||||.|||..|.....|.::||.::|.|.:|::|
Human    83 ------------------RRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIW 129

  Fly   246 FQNRRMKHKRQ 256
            |||:|.|.::|
Human   130 FQNQRAKWRKQ 140

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	27/55 (49%)
ISX	NP_001290437.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	38..86		15/85 (18%)
		Homeodomain	83..139	CDD:459649	27/55 (49%)