Protein Alignment pb and BARX2

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_003649.2
• Gene: BARX2 / 8538
• HGNCID: 956
• Length: 279
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 64/251 - (25%)
• Similarity: 102/251 - (40%)
• Gaps: 66/251 - (26%)

  Fly    70 PSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESPKIGTPVGSGAIGGVG 134
            ||:::..|...:|....:..||.:.:    .|..||::   ::||.|.:|.|...:...
Human    49 PSLVVRPKPLHSCTGSPSLRAYPLLS----VITRQPTV---ISHLVPATPGIAQALSCH------ 100

  Fly   135 VNVNVNVGVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPR 199
               .|...|....|.|   :.....:|..|.|..::||                         ||
Human   101 ---QVTEAVSAEAPGG---EALASSESETEQPTPRQKK-------------------------PR 134

  Fly   200 RLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTL------ 258
            |.||.:|..||:.|||:|...|||..|.|:::|.||.||:.|||.|:||||||.|:..|
Human   135 RSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEA 199

  Fly   259 ----------------SKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIP 298
                            .:.:.|:..:|.....:|.:.:...::.|:..|..:.|:|
Human   200 PTKPKGRPKKNSIPTSEEIEAEEKMNSQAQGQEQLEPSQGQEELCEAQEPKARDVP 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	31/55 (56%)
BARX2	NP_003649.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..137		10/54 (19%)
		Homeodomain	134..190	CDD:459649	31/55 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..279		7/62 (11%)