Protein Alignment pb and Nkx6-3

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_083278.1
• Gene: Nkx6-3 / 74561
• MGIID: 1921811
• Length: 262
• Species: Mus musculus
• Alignment Length: 248
• Identity: 66/248 - (26%)
• Similarity: 90/248 - (36%)
• Gaps: 79/248 - (31%)

  Fly    59 PGIGQQ---GVP-PVPSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESP 119
            ||:|.|   |.| .:..:|.....|||                ...::..|.:|
Mouse    41 PGLGPQLAAGTPHGITDILSRPVATPN----------------SSLLSGYPHVA----------- 78

  Fly   120 KIGTPVGSGAIGGVGVNVNVNVG----VGVGYPVGVVPQTPD-GMDSVPEYPWMKEKKTSRKSSN 179
                  |.|.:...||.....||    .|..||........| |.|      |   :.::|..||
Mouse    79 ------GFGGLSSQGVYYGPQVGSFSKAGNEYPTRTRNCWADTGQD------W---RGSARPCSN 128

  Fly   180 NNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKV 244
            ..:...::|.:       .:..|..:|..|:..|||.|...|||..|.|..:|.||.:||.||||
Mouse   129 TPDPLSDTIHK-------KKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKV 186

  Fly   245 WFQNRRMKHKRQTL----SKT-----------------DDEDNKDSLKGDDDQ 276
            ||||||.|.::::.    |.|                 |||.||......||:
Mouse   187 WFQNRRTKWRKKSALEPSSSTPRAPGGASGDRAASENEDDEYNKPLDPDSDDE 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	28/55 (51%)
Nkx6-3	NP_083278.1	Homeodomain	139..197	CDD:459649	28/64 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..237		7/39 (18%)