Protein Alignment pb and Nkx6-3

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001102925.1
• Gene: Nkx6-3 / 685102
• RGDID: 1597780
• Length: 262
• Species: Rattus norvegicus
• Alignment Length: 249
• Identity: 64/249 - (25%)
• Similarity: 93/249 - (37%)
• Gaps: 81/249 - (32%)

  Fly    59 PGIGQQ---GVP-PVPSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESP 119
            ||:|.|   |.| .:..:|.....|||                ...::..|.:|.|
  Rat    41 PGLGPQLAAGTPHGITDILSRPVATPN----------------SSLLSGYPHVAGF--------- 80

  Fly   120 KIGTPVGSGAIGGVGVNVNVNVGVGVGYPVGVVPQTPDGMDSVPEYP------WMKEKKTSRKSS 178
                       ||:.     :.||..|..||...:|.:      |||      |....:..|.|:
  Rat    81 -----------GGLS-----SQGVYYGPQVGSFSKTGN------EYPTRTRNCWADTGQDWRGST 123

  Fly   179 NNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVK 243
            ...:...:.:::.:.:.   :..|..:|..|:..|||.|...|||..|.|..:|.||.:||.|||
  Rat   124 RPCSNTPDPLSDTIHKK---KHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVK 185

  Fly   244 VWFQNRRMKHKRQTL----SKT-----------------DDEDNKDSLKGDDDQ 276
            |||||||.|.::::.    |.|                 |||.||......||:
  Rat   186 VWFQNRRTKWRKKSALEPSSSTPRAPGGASGDRAASENEDDEYNKPLDPDSDDE 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	28/55 (51%)
Nkx6-3	NP_001102925.1	Homeodomain	139..197	CDD:459649	28/60 (47%)