Protein Alignment pb and Vax1

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_072158.1
• Gene: Vax1 / 64571
• RGDID: 621132
• Length: 336
• Species: Rattus norvegicus
• Alignment Length: 290
• Identity: 69/290 - (23%)
• Similarity: 104/290 - (35%)
• Gaps: 85/290 - (29%)

  Fly   174 SRKSSNNNNQGD-----------NSITEFVPENGL----PRRLRTAYTNTQLLELEKEFHFNKYL 223
            ::..||::...|           .||.|.:...||    |:|.||::|..||..||.||...:|:
  Rat    61 NKSKSNSSADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYV 125

  Fly   224 CRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQ 288
            ....|.|:|..|:|:|.||||||||||.|.|:        :..|||     :.....|.:..:|.
  Rat   126 VGRERTELARQLNLSETQVKVWFQNRRTKQKK--------DQGKDS-----ELRSVVSETAATCS 177

  Fly   289 ----------------------------GCELPSDDIP-----------------DSTSNSRGHN 308
                                        |..|....:|                 .:.....|..
  Rat   178 VLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAAAAAATAPGPAGAA 242

  Fly   309 NNTPSATNNNPSAGNLTPNSSLETGISSNLMGSTTVSASNVISADSSVASSVSLDEDIEESSPIK 373
            :..|.|....|..|...| ..|..|..:...|..::...:::   .||||.:|       |:|:.
  Rat   243 SQHPPAVGGAPGPGPAGP-GGLHAGAPTASHGLFSLPVPSLL---GSVASRLS-------SAPLT 296

  Fly   374 VKKKDDGQVIKKEAVSTSSKA-SPFGYENS 402
            :.....|.:.:..|...||.| .|:...|:
  Rat   297 MAGSLAGNLQELSARYLSSSAFEPYSRTNN 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	28/55 (51%)
Vax1	NP_072158.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..39
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	50..69		2/7 (29%)
		vax upstream domain	72..99		6/26 (23%)
		homeobox	100..159		30/66 (45%)
		Homeodomain	101..157	CDD:459649	28/55 (51%)
		vax downstream domain	178..189		0/10 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	236..267		7/31 (23%)
		vax terminal domain	315..323		3/7 (43%)