Protein Alignment pb and nkx2.4b

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_571664.1
• Gene: nkx2.4b / 58112
• ZFINID: ZDB-GENE-000830-1
• Length: 307
• Species: Danio rerio
• Alignment Length: 294
• Identity: 78/294 - (26%)
• Similarity: 110/294 - (37%)
• Gaps: 78/294 - (26%)

  Fly    90 AYWMTASE------GGFINSQ-------PSMAEFLNHLSPESPKIGTPVGSGAIGGVGVN----- 136
            ||.|..|:      ||:.|..       ||..|.:.:            |:.|....|.|
Zfish    60 AYHMPHSQFSHSTMGGYCNGTIGAMGDLPSYQESMRN------------GATATAWYGSNPEPRY 112

  Fly   137 --VNVNVGVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPR 199
              ::..:|...|..:|.:|    |||             :.||             .|..:..||
Zfish   113 PTISRFMGPSAGMNMGTLP----GMD-------------ASKS-------------MVTLHAAPR 147

  Fly   200 R-LRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDD 263
            | .|..::..|:.|||:.|...|||..|.|..:|:.:.||..|||:||||.|.|.|||.
Zfish   148 RKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQA------ 206

  Fly   264 EDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNS 328
               ||  |....|...|..:::|.:...||. .:.|......|....||.........|:.|..|
Zfish   207 ---KD--KASQQQDSGNMCAQQSPRRVALPV-LVKDGKPCQNGSGTPTPIHQQVQSVLGSETLAS 265

  Fly   329 S---LETGISSNLMGSTTVSASNVISADSSVASS 359
            :   .|...|..|||..:.:.:.:|...||:.||
Zfish   266 AEDLEEMSPSPPLMGGLSQTDAALIEYTSSMVSS 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	25/56 (45%)
nkx2.4b	NP_571664.1	Homeodomain	148..204	CDD:459649	24/55 (44%)