Protein Alignment pb and pb

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: XP_061500970.1
• Gene: pb / 5667717
• VectorBaseID: AGAMI1_011971
• Length: 790
• Species: Anopheles gambiae
• Alignment Length: 924
• Identity: 342/924 - (37%)
• Similarity: 438/924 - (47%)
• Gaps: 276/924 - (29%)

  Fly     1 MQEVCSSLDTTSMGTQIKSESP-LNPLQVQTGQTSLPVGGCGGAGVVG------GVGGVGVSVGQ 58
            |||||:||:  .||.||||||| :..|.|            |.|.|||      ....|.::..|
Mosquito     1 MQEVCNSLE--HMGAQIKSESPAIGSLHV------------GTAVVVGSETDITNAQQVSLTTNQ 51

  Fly    59 PGIGQQGVPPVPSVLMVNKMTPNCDK-------------------------------RSADTAYW 92
                ||......|..::.:....|||                               |.|||:||
Mosquito    52 ----QQQTIIAGSTQLIGRKQVICDKTTRVATQLSVITSVEPLGAQAATQQQPHQQQRIADTSYW 112

  Fly    93 MTASEGGFINSQPSMAEFLNHLSPESPKIGTPVGSGAIGGVGVNVNVNVGVGVGYPVGVVPQTPD 157
            | .:|.|||||||||||||.|:..||||:.|.                     |.|:|    ..|
Mosquito   113 M-QNESGFINSQPSMAEFLTHIDSESPKLVTQ---------------------GIPIG----PSD 151

  Fly   158 GMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKY 222
            .|:|||||||||||||:||::        :..|||.|||||||||||||||||||||||||||||
Mosquito   152 NMESVPEYPWMKEKKTARKAT--------AQAEFVAENGLPRRLRTAYTNTQLLELEKEFHFNKY 208

  Fly   223 LCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSC 287
            |||||||||||||||||||||||||||||||||||||||||:::     |.||..|  |||||||
Mosquito   209 LCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDDES-----GKDDLKD--SNSKKSC 266

  Fly   288 QGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSNLMGSTTVSASNVISA 352
            |||||||||||||||:|||.|||||:..        :||||:::....:...|||: ..:|.:||
Mosquito   267 QGCELPSDDIPDSTSSSRGMNNNTPNTV--------MTPNSTIDISTPTGGGGSTS-GGTNAVSA 322

  Fly   353 DSSVASSVSLDEDIEESSPIKVKKKDDGQVIKKEAVSTS--SKASPF-GYENSTPSLVSFRRDSD 414
            ||||||:.|:||  |:....|||||.|  .||||:||::  |.::.| .|:||     .:.:|
Mosquito   323 DSSVASTDSIDE--EDDVHAKVKKKSD--AIKKESVSSTKVSNSNSFKSYDNS-----GYPKD-- 376

  Fly   415 ASAVGNAPTSKAVGKKRFQSAANAIATPTPLSDSNSGNGSGG----------------------- 456
             :.:.:.|.|.|:.......:::|| :||...:||:.|.:..
Mosquito   377 -NGLISGPPSAAIPIPHSPVSSSAI-SPTNNINSNNNNSNNNNNLQLYYNHPNHSYGVIKHKCPP 439

  Fly   457 ---------------GPAGGYFPGYYPSPKQQQQVQQQQ--LHPQQQQLPQQQP----------- 493
                           ||:.|   |.|.:.|||:...:.:  ||.|......|:.
Mosquito   440 GPVIGHEIEGSPATTGPSAG---GIYFNNKQQEYFSKTECGLHYQPSYQHYQKTVVPPGAIYTNT 501

  Fly   494 -----QDYYGKYDIEFAASPHHNPHNKQQALHGEYLSPKP----SSANFHQNSQQQQQNDHFYYN 549
                 ..|.|...|::         |..|:|.|  .|.||    :|...|.  |||.|||..:.:
Mosquito   502 QHILNDSYQGAQKIDY---------NPAQSLKG--FSTKPLVQDNSQKLHH--QQQMQNDPTFQS 553

  Fly   550 YNDTNGTPYLNHQQQHHHHA-QHHQQQQHHQNHVADFEGPVNGPSNF---------NNGAYYDNM 604
            .|.    |:.|.....|:.| |:....||:.::..|.:....|.:.:         ....|||:|
Mosquito   554 QNQ----PFYNSCDTGHNGAGQYVPSGQHYYSNDYDPQHEFGGGTGYYEHTKMSLVGQNHYYDSM 614

  Fly   605 SFQQQAQAHQHQTVVFQQQQPHQPAAINHQHMHHLGNGETYSAL------GLQMENCEGYNNFGA 663
            .      :.||.||.            ::.:|.:.||. .|:.:      |:..|:||.|....:
Mosquito   615 G------SFQHNTVA------------SNNNMEYQGNA-PYAGIDAALPGGIGNESCESYAFHQS 660

  Fly   664 AGTGGGYYEAGQQPPIPATHGHGHHP----HHVQVPAQAHA---------PIHAHHNSAAIPG-- 713
            :.....|||  ||      |.|..|.    ||.|...|.|:         ....|.|...:.|
Mosquito   661 SHLASAYYE--QQ------HQHQQHQSQQNHHHQHAFQHHSIQQLQVFPHQQQTHSNPTGVSGVN 717

  Fly   714 GVGVGPPPSHIHGF---------AINGGPAVQGQAFGNNGSTA-AGTAAISGLENSNSSDFNFLS 768
            ...|....:||...         :.||.|.      |::.||. :..||:..::|||||||||||
Mosquito   718 NATVAKTTTHIENHHDITTGEHCSFNGCPP------GSSTSTTQSKAAAMVSMDNSNSSDFNFLS 776

  Fly   769 NLANDFAPEYYQLS 782
            ||||||||||||||
Mosquito   777 NLANDFAPEYYQLS 790

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	55/55 (100%)
pb	XP_061500970.1	None