Protein Alignment pb and nkx6.2

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001129256.1
• Gene: nkx6.2 / 565782
• ZFINID: ZDB-GENE-070626-1
• Length: 278
• Species: Danio rerio
• Alignment Length: 277
• Identity: 71/277 - (25%)
• Similarity: 110/277 - (39%)
• Gaps: 71/277 - (25%)

  Fly    54 VSVGQPGIGQQ-----GVPPVPSVLMVNKMTPNCDKRSADTAYWMTA--SEGGFINSQPSMAEFL 111
            ::|||....:|     |..|:.::..:.:|         .|:.:..|  |..||  ..||    |
Zfish     2 LAVGQMDSNRQSAFVLGSTPLAALHNMTEM---------KTSLFPYALQSPAGF--KAPS----L 51

  Fly   112 NHLSPESPKIGTPVGSGAIGGVGVNV---------NVN---VGVGVGYPVGVVPQTPDGMDSVP- 163
            .:|:.:.| :|||.|...|.|..:..         .:|   ...|:.:....|.:.|..:..:|
Zfish    52 GNLNSQIP-LGTPHGISDILGRPITTAGQLLSGFPRINGLATSAGMYFNPAAVSRYPKPLTELPG 115

  Fly   164 -----------EYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEF 217
                       ..||...:......:|          ..:.::|..:..|..::..|:..|||.|
Zfish   116 RAPIFWPGMMQGSPWRDPRVPCAAQAN----------MMLDKDGKKKHSRPTFSGQQIFALEKTF 170

  Fly   218 HFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQ------TLSKTDD---EDNKDSLKGD 273
            ...|||..|.|..:|.||.:||.||||||||||.|.:::      |..|..|   |..|:|...|
Zfish   171 EQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMATAKKKHDSETEKMKESSDND 235

  Fly   274 DDQS-----DSNSNSKK 285
            :|..     |.||:.:|
Zfish   236 EDDEYNKPLDPNSDDEK 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	27/55 (49%)
nkx6.2	NP_001129256.1	Homeodomain	150..208	CDD:459649	27/57 (47%)