Protein Alignment pb and nkx2.4a

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001104636.1
• Gene: nkx2.4a / 562300
• ZFINID: ZDB-GENE-030131-6336
• Length: 345
• Species: Danio rerio
• Alignment Length: 372
• Identity: 83/372 - (22%)
• Similarity: 125/372 - (33%)
• Gaps: 125/372 - (33%)

  Fly    30 TGQTSLPVGGCGGAGVVGGVGGVGVSVGQPGIGQQGVPPVPSVLMVNKMTPNCDKRSADTAYWMT 94
            ||..:.|:|                :..||.:.|.|       :..:.|..|.   :..|.|.|.
Zfish    33 TGNLTSPLG----------------AYRQPQVSQTG-------MQQHSMGHNA---TVATTYHMP 71

  Fly    95 --------ASEGGFINSQ-------PSMAEFLNHLSPESPKIGTPVGSGAIGGVGVNVNVNVGVG 144
                    ::.||:.|..       ||..|.:.:            .:.|.|..|.|
Zfish    72 HSVSQFSHSAMGGYCNGSIANMGDLPSYQETMRN------------SAAATGWYGAN-------- 116

  Fly   145 VGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSIT-------EFVPENGLPRR-L 201
                       ||     |.|..:  .:....|:..|..|..::|       ...|.:..||| .
Zfish   117 -----------PD-----PRYSTI--SRFMGPSTGMNMTGMGTLTGMADTTKSIPPLHAAPRRKR 163

  Fly   202 RTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDN 266
            |..::..|:.|||:.|...|||..|.|..:|:.:.||..|||:||||.|.|.|||...|...:..
Zfish   164 RVLFSQAQVCELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQ 228

  Fly   267 KDSLKGDDDQSDSN------SNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLT 325
            ::.......||...      ....|.||                  :.:|||            |
Zfish   229 QEGNLCQQQQSPRRVAVPVLVKDGKPCQ------------------NGSNTP------------T 263

  Fly   326 PNSSLETGISSNLMGSTTVSASNVISA-DSSVASSVSLDEDIEESSP 371
            ||.. :.....|..|....::||.::. .|...:::...:|:||.||
Zfish   264 PNQQ-QMQQQQNGGGVVLPTSSNSMNQHQSQQVNALVQAQDLEEMSP 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	25/56 (45%)
nkx2.4a	NP_001104636.1	Homeodomain	161..217	CDD:459649	24/55 (44%)