Protein Alignment pb and BARX1

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_067545.3
• Gene: BARX1 / 56033
• HGNCID: 955
• Length: 254
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 70/271 - (25%)
• Similarity: 109/271 - (40%)
• Gaps: 61/271 - (22%)

  Fly    57 GQPGIGQQGVPP---------VPSVLMVNKMT-PNCDKRSADTAYWMTASEGGFINSQPSMA--E 109
            |:||..:.|.|.         ..|.::...:| |...|.:|..|....|.|......|..:|  .
Human     5 GEPGAARFGPPEGCADHRPHRYRSFMIEEILTEPPGPKGAAPAAAAAAAGELLKFGVQALLAARP 69

  Fly   110 FLNHLS------------PESPKIGTPVGSGAIGGVGVNVNVNVGVGVGYPVGVVPQTPDGMDSV 162
            |.:||:            |.:|          :|..|:: :..:..|.|.|         |....
Human    70 FHSHLAVLKAEQAAVFKFPLAP----------LGCSGLS-SALLAAGPGLP---------GAAGA 114

  Fly   163 PEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPR 227
            |..|...:.:...:::.....|..:      :.|  ||.||.:|..||:.|||.|...|||..|.
Human   115 PHLPLELQLRGKLEAAGPGEPGTKA------KKG--RRSRTVFTELQLMGLEKRFEKQKYLSTPD 171

  Fly   228 RIEIAASLDLTERQVKVWFQNRRMKHKRQTL--------SKTDDEDNKDSLKGDDDQSDSNSNSK 284
            ||::|.||.|::.|||.|:||||||.|:..|        :|......|:|:. ..:|......:|
Human   172 RIDLAESLGLSQLQVKTWYQNRRMKWKKIVLQGGGLESPTKPKGRPKKNSIP-TSEQLTEQERAK 235

  Fly   285 KSCQGCELPSD 295
            .:.:..|:|.:
Human   236 DAEKPAEVPGE 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	31/55 (56%)
BARX1	NP_067545.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		5/14 (36%)
		Homeodomain	143..199	CDD:459649	31/55 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..254		7/44 (16%)