Protein Alignment pb and E5

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 646
• Identity: 134/646 - (20%)
• Similarity: 185/646 - (28%)
• Gaps: 297/646 - (45%)

  Fly    18 KSESPLNPLQVQTGQTSLPVG----------------------------GCGG----AGVVGGVG 50
            :||||.:|..........|.|                            ..||    ||.....|
  Fly    79 RSESPASPTNTNNSGRRTPRGYIYCRRRDSLDRSRSPQRSPVSRSPSPPNAGGNPAAAGNTAKSG 143

  Fly    51 GVGVSVGQPGIGQQGVP-PVPSVLMV-NKMTPNCDKRSADTAYWMTASEGG----------FINS 103
            ......|.|....:.:| |.|::.:: |:.:||.          |.....|          |:.:
  Fly   144 DPSSGTGNPPTLIRPLPLPAPNLALIGNRTSPNA----------MAVRMAGPPHPPSQPPPFLAA 198

  Fly   104 QPSMAEFLNH----LSPESPKIGTPVGSGAIGGVGVNV---NVNVGVGVG------------YPV 149
            |..||..|.|    ...:..:...||.:|...|...::   .:.:|:..|            :|.
  Fly   199 QFQMAAALAHHHQQQQQQQQQQLPPVPTGPPHGPHPHLPPGQIPLGIFPGGPHPGHPPPHGHHPF 263

  Fly   150 GVVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGL------PRRLRTAYTNT 208
            |..|...  .||.|.|||:..:             ...|....|.|.|      |:|:|||::.|
  Fly   264 GSAPHLI--RDSYPLYPWLLSR-------------HGRIFPRFPGNFLFQPFRKPKRVRTAFSPT 313

  Fly   209 QLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDED---NKDSL 270
            |||:||..|..|.|:....|.::|..|.|||.||||||||||.||||......|..|   ||.|.
  Fly   314 QLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKRMQQEGGDGSDTKSNKGSS 378

  Fly   271 K-----GDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSL 330
            .     ||.:....:..|:.|.:..|.|.|
  Fly   379 SGGGGGGDGEDDAKHDGSQHSYEDAEDPED----------------------------------- 408

  Fly   331 ETGISSNLMGSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKDDGQVIKKEAVSTSSKAS 395
                                            :::|||....:|...||
  Fly   409 --------------------------------EDEIEEDDEDEVIDMDD---------------- 425

  Fly   396 PFGYENSTPSLVSFRRDSDASAVGNAPTSKAVGKKRFQSAANAIATPTPLSDSNSGNGSGGGPAG 460
             :|.|            .||
  Fly   426 -YGSE------------MDA--------------------------------------------- 432

  Fly   461 GYFPGYYPSPKQQQQVQQQQLHPQQQQLPQQQPQDYYGKYDIEFAASPHHNPHNKQQALHGEYLS 525
                      ::.|::::|    .||||.|.|.|                  ..:|.|.....||
  Fly   433 ----------EEHQRLREQ----FQQQLAQHQQQ------------------FMQQNAGEAATLS 465

  Fly   526 PKPSSANFHQNSQQQQQNDHFYYNYNDTNGTPYLNHQQQHHHHAQHHQQQQHHQNHVADFE 586
            |:..    ||..||.||                  |.||.||..|.|..||..|.::.:.|
  Fly   466 PQQQ----HQLLQQHQQ------------------HLQQQHHQQQQHFIQQQQQLYLRERE 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	31/55 (56%)
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	31/55 (56%)