Protein Alignment pb and MEOX2

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_005915.2
• Gene: MEOX2 / 4223
• HGNCID: 7014
• Length: 304
• Species: Homo sapiens
• Alignment Length: 240
• Identity: 82/240 - (34%)
• Similarity: 110/240 - (45%)
• Gaps: 64/240 - (26%)

  Fly   101 INSQPSMAEFLNHLSPES---PKIGT--PV---GSGAIGGVGVNVNVNVGVGVGYPVGVVPQTPD 157
            ::|.||.|.....|.|:|   |::|:  ||   .|.::|.                     .||.
Human    97 MSSPPSAARHSLCLQPDSGGPPELGSSPPVLCSNSSSLGS---------------------STPT 140

  Fly   158 GMDSVP-EY------PWMKEKKT--SRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLEL 213
            |....| :|      |...||::  .|||.::::|..|..:|.   |..||:.|||:|..|:.||
Human   141 GAACAPGDYGRQALSPAEAEKRSGGKRKSDSSDSQEGNYKSEV---NSKPRKERTAFTKEQIREL 202

  Fly   214 EKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSD 278
            |.||..:.||.|.||.|||.:||||||||||||||||||.||.          |...:|...:..
Human   203 EAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRV----------KGGQQGAAAREK 257

  Fly   279 SNSNSKKSCQGCELPSD----------DIPDSTSNSRGHNNNTPS 313
            ...|.||   |..|||:          ...||.:|...|:::..|
Human   258 ELVNVKK---GTLLPSELSGIGAATLQQTGDSIANEDSHDSDHSS 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	37/55 (67%)
MEOX2	NP_005915.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..192		30/118 (25%)
		COG5576	160..284	CDD:227863	58/139 (42%)
		Homeodomain	188..244	CDD:459649	37/55 (67%)