Protein Alignment pb and MEOX1

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 91/282 - (32%)
• Similarity: 117/282 - (41%)
• Gaps: 74/282 - (26%)

  Fly    32 QTSLPVGGCGGAGVVGGVGGVGVSVGQP---GIGQQGVPPVPSVLMVNKMTPNCDKRSADTAYWM 93
            |...||.||               :..|   |.|..|:|..|.       ||....:..|.....
Human    13 QPPAPVWGC---------------LRNPHSEGNGASGLPHYPP-------TPFSFHQKPDFLATA 55

  Fly    94 TASEGGF----INSQPSMAEFLNHL-------SPESPKIGTPV-------GSGAIGG---VGVN- 136
            ||:...|    :.:.|.......|:       .|:||....||       .||..||   :|.:
Human    56 TAAYPDFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSS 120

  Fly   137 ---VNVNVGVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRK----SSNNNNQGDNSITEFVPE 194
               |:...|.|..|  ||:..|.:          ..|||:||:    |.|..|:|.       ||
Human   121 LGLVDTTGGPGDDY--GVLGSTAN----------ETEKKSSRRRKESSDNQENRGK-------PE 166

  Fly   195 -NGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTL 258
             :...|:.|||:|..||.|||.||..:.||.|.||.|||.:|||:||||||||||||||.||...
Human   167 GSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKG 231

  Fly   259 SKTDDEDNKDSLKGDDDQSDSN 280
            .:....:.:|...||...|.|:
Human   232 GQPISPNGQDPEDGDSTASPSS 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	37/55 (67%)
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		31/110 (28%)
		Homeodomain	172..228	CDD:459649	37/55 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		7/27 (26%)