Protein Alignment pb and Dfd

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Alignment Length: 562
• Identity: 135/562 - (24%)
• Similarity: 187/562 - (33%)
• Gaps: 252/562 - (44%)

  Fly    12 SMGTQIKSESPLNPL-------------QVQTGQTSLPVGGCGGAGVVGGVGGVGVSVGQPGIGQ 63
            |||..:..:.|  ||             ...||..|..|||..|.|.||| ||.|...|.|
  Fly    20 SMGNGLDPKFP--PLADDYHHYNGHYSMTASTGHMSGAVGGGAGVGSVGG-GGAGGMTGHP---- 77

  Fly    64 QGVPPVPSV--LMVNKMTPNCDKRS---------ADTAY--WMTASEGG----FINSQP------ 105
            ..:.|...|  .|.:...|:....|         :::|.  ...||.||    :.|:.|
  Fly    78 HSMHPADMVSDYMAHHHNPHSHSHSHTHSLPHHHSNSAISGHHQASAGGYSSNYANATPPSHPHS 142

  Fly   106 --------SMAEFLNHLSPE---------------SPKIGTP--------VGSGAI---GGVGVN 136
                    |:..:::| :||               .|....|        .||||:   |.||.:
  Fly   143 HPHAHPHQSLGYYVHH-APEFISAGAVHSDPTNGYGPAANVPNTSNGGGGGGSGAVLGGGAVGGS 206

  Fly   137 VN-VNVGVGVGY----------------------------------------------------- 147
            .| ...|.|.||
  Fly   207 ANGYYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIE 271

  Fly   148 ---PVG----------------------------VVPQTPDGM----------------DSVPE- 164
               |.|                            ::.::||.:                |.:.|
  Fly   272 EAVPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAET 336

  Fly   165 -------YPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKY 222
                   |||||:...:..::.:...|..           |:|.|||||..|:||||||||:|:|
  Fly   337 TDGERIIYPWMKKIHVAGVANGSYQPGME-----------PKRQRTAYTRHQILELEKEFHYNRY 390

  Fly   223 LCRPRRIEIAASLDLTERQVKVWFQNRRMKHK--------RQTLSKTDDEDNKD----------- 268
            |.|.||||||.:|.|:|||:|:||||||||.|        :....||.|.:...
  Fly   391 LTRRRRIEIAHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGNPTPVAKKPTKRA 455

  Fly   269 -SLKGDDDQSDSNSNSKKSCQ-----GCELPSDDI-------------------PDSTSNSRG-- 306
             |.|....|....|..:::.|     .| :.||.:                   |::||:..|
  Fly   456 ASKKQQQAQQQQQSQQQQTQQTPVMNEC-IRSDSLESIGDVSSSLGNPPYIPAAPETTSSYPGSQ 519

  Fly   307 ----HNNNTPSATNNNPSAGNLTPNSSLETGISSNLMGSTTV 344
                :|||..|..|||.:..|   ||:|....::|.||.|.:
  Fly   520 QHLSNNNNNGSGNNNNNNNNN---NSNLNNNNNNNQMGHTNL 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	40/63 (63%)
Dfd	NP_477201.1	Homeodomain	367..423	CDD:459649	39/55 (71%)