Protein Alignment pb and pitx3

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_991238.1
• Gene: pitx3 / 402974
• ZFINID: ZDB-GENE-041229-4
• Length: 293
• Species: Danio rerio
• Alignment Length: 271
• Identity: 76/271 - (28%)
• Similarity: 114/271 - (42%)
• Gaps: 56/271 - (20%)

  Fly   163 PEY-PWMKEKKTSRKSSNNNNQGDNSITEFVPENG----LPRRLRTAYTNTQLLELEKEFHFNKY 222
            |:: |..|.:..|....::.|..|.|    .||:|    ..||.||.:|:.||.|||..|..|:|
Zfish    24 PQHDPGCKGQDNSDTEKSHQNHTDES----NPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRY 84

  Fly   223 LCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNS-KKS 286
            .....|.|||...:|||.:|:|||:|||.|.:::       |.|:        |::...|. ...
Zfish    85 PDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKR-------ERNQ--------QAELCKNGFGAQ 134

  Fly   287 CQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTP--NSSLETGISSNLMGSTTVSASNV 349
            ..|...|.||:....|    :||....:..::|.:....|  ||...:.:||..|.|...|..::
Zfish   135 FNGLMQPYDDMYSGYS----YNNWATKSLASSPLSAKSFPFFNSMNVSPLSSQPMFSPPSSIPSM 195

  Fly   350 ISADSSVASSV---------SLDEDIEESSPIKVKKKDDGQVIKKEAVST-----SSKASPFGYE 400
            ..|.|.|.|:|         :|......:||          .:...|||.     ::.|.|:.|.
Zfish   196 NMASSMVPSAVAGVPGSGLNNLGNLNNLNSP----------TLNSAAVSAAACPYATTAGPYMYR 250

  Fly   401 NS-TPSLVSFR 410
            :: ..||.|.|
Zfish   251 DTCNSSLASLR 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	28/55 (51%)
pitx3	NP_991238.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..69		14/48 (29%)
		Homeodomain	61..117	CDD:459649	28/55 (51%)
		OAR	251..268	CDD:461067	4/11 (36%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	255..268		4/7 (57%)
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:O35160	260..264		1/2 (50%)