Protein Alignment pb and Dll

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Alignment Length: 493
• Identity: 102/493 - (20%)
• Similarity: 144/493 - (29%)
• Gaps: 214/493 - (43%)

  Fly   115 SPESPKIGTPVGSGAIGGVGVN-------VNVNVGVGVGYPVGVVPQT------PDGMDS-VPE- 164
            :|.:||......:.|....|:|       |.:......||  |.:..|      ..|.|| .|.
  Fly     6 APHTPKYMDGGNTAASVTPGINIPGKSAFVELQQHAAAGY--GGIRSTYQHFGPQGGQDSGFPSP 68

  Fly   165 -----YPWMKEKKTSRKSSNNNN---------QGDNSITEFVPENGL--------PRRLRTAYTN 207
                 ||:....:.|....:..:         :.|.||::...::||        .|:.||.|::
  Fly    69 RSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSS 133

  Fly   208 TQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKG 272
            .||.:|.:.|...:||..|.|.|:||||.||:.|||:||||||.|:|:.
  Fly   134 LQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKM---------------- 182

  Fly   273 DDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSN 337
                       .|:.||               .|.|:..|.. ...|:.|..:||.
  Fly   183 -----------MKAAQG---------------PGTNSGMPLG-GGGPNPGQHSPNQ--------- 211

  Fly   338 LMGSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKDDGQVIKKEAVSTSSKASPFGYENS 402
             |.|..::....:.|                                  |:.|          |.
  Fly   212 -MHSGELANGRFLWA----------------------------------ALET----------NG 231

  Fly   403 TPSLVSFRRDSDASAVGNAPTSKAVGKKRFQSAANAIATPTPLSDSNSGNGSGGGPAGGYFPGYY 467
            |.:||.       |..||                            |.|..:.|.|:....||:.
  Fly   232 TLALVH-------STGGN----------------------------NGGGSNSGSPSHYLPPGHS 261

  Fly   468 PSPKQQQQVQ-QQQLHPQQQQLPQQQPQDYYGKYDIEFAASPHHNPHNKQQALHGEYLSPKPSSA 531
            |:|......: ..:..|.....|.|.|.|          ..||...|           .|.|
  Fly   262 PTPSSTPVSELSPEFPPTGLSPPTQAPWD----------QKPHWIDH-----------KPPP--- 302

  Fly   532 NFHQNSQQQQQNDHFYYNYNDTNGTPYLN-HQQQHHHH 568
                  |...|..|           |... |.|.|||:
  Fly   303 ------QMTPQPPH-----------PAATLHPQTHHHN 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	29/55 (53%)
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	29/55 (53%)