Protein Alignment pb and Rx

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_726006.3
• Gene: Rx / 37367
• FlyBaseID: FBgn0020617
• Length: 904
• Species: Drosophila melanogaster
• Alignment Length: 849
• Identity: 172/849 - (20%)
• Similarity: 273/849 - (32%)
• Gaps: 269/849 - (31%)

  Fly   114 LSPESPKIGTPVG-----SGAIGGVGVNVNVNVGVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKT 173
            ::|..|  |:|.|     |||:.|.|               ||.                  ..:
  Fly    13 VAPGQP--GSPAGKPVAISGAMSGSG---------------GVA------------------NSS 42

  Fly   174 SRKSSNNNNQGDNSITEFVPENG-----LPRR-----------LRTAYTNTQLLELEKEF----- 217
            |..::||.......|.|.:.:.|     ||.:           :|.|.....::|..|..
  Fly    43 STAAANNTAATFQHIFEQLVQQGGGNHKLPPKQLEQLRHLLGNVRDAKNLQMIVEKFKNLEQFHE 107

  Fly   218 HFNKYLCRPRR-IEIAASLDLTERQVKVWFQNRRMKHKRQTLS-------------------KTD 262
            |:..:|..... |....|.||.:...:.:....:....|.|:.                   :|.
  Fly   108 HYAAHLANNNTVISTEDSNDLVKDNARKYGSGGQTLTPRHTIDAILGLKNRNGAANGSGRNPETV 172

  Fly   263 DEDNKDSLKGDDDQSD-----------SNSNSKKSC------QGCELP----------SDDIPDS 300
            .:.:.|...||||.:|           |..|...|.      .|..||          ...:|::
  Fly   173 SDGSVDPSLGDDDATDLRCGMTLTQLRSMDNHMASMLQQHAKNGGALPYGPPTPPGGQQPQVPNA 237

  Fly   301 TSNSRG-------------------HNNNTPSATNN--------------NPSAGNLTPNSSLET 332
            |....|                   |:.:.|...:|              ..:|||..  :|:..
  Fly   238 TPLHHGQQMGGQAGHATHAGHGHPTHHGHAPFGYHNAFGFGQGGHGYGHPEEAAGNYL--NSMHQ 300

  Fly   333 GISSNLMGSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKDDGQVIKKEAVSTSSKASP- 396
            .:.:|.: .|..:.:|...|....:|..|..:.:   :.:..:.::......|.|.|:.:.|.|
  Fly   301 MVEANQL-QTGANGANPPPAPLPPSSFGSHQQHL---AALAAQAQEQQNQHSKYAKSSPTGAGPP 361

  Fly   397 -----FGYENST----PSLVSF------------RRDSDASAVGNAPTSKAVGKKRFQSAANAIA 440
                 :..|:.|    ||.:::            ..|.||:.:....||......|.|.||...:
  Fly   362 PPPGAYFMESQTAPVAPSQINYDERSMSSASDLEEDDDDAAKLQLDVTSPPTPSPRGQLAAKRKS 426

  Fly   441 TPTPLSDSNSGNGSGGGPAGGYFPGYYPSPKQQQQVQQQQLHPQQQQLPQQQPQDYYGK--YDIE 503
            ......|:.....:|..|.|.|  |..|...::...|||..|.||||..|||.|....:  :..:
  Fly   427 AGVFCDDNEPKLANGQLPGGNY--GIRPRSMEEVHHQQQSHHHQQQQQQQQQQQQLQQQQGFQHD 489

  Fly   504 FAASPHHNPH-NKQQALHGEYLSPK---------PSSANFHQNSQQQQ------------QNDHF 546
            |..|.:.||: |.....|||.|:..         .||.:.:|.:..:|            |:|:.
  Fly   490 FRNSGNGNPNGNSNSGDHGERLNADSDSLVNGSCASSEDLNQTNSSEQGEKITSGSDDEGQDDNC 554

  Fly   547 YYNYNDTNGTPYLNHQQQHHHHAQHHQQQQHHQNHVADFEG------PVNGPSNFNNGAYYDN-- 603
            ....:..|.|.:..:|       .|..::...::|..|...      .||.| ......::.|
  Fly   555 AKKKHRRNRTTFTTYQ-------LHELERAFEKSHYPDVYSREELAMKVNLP-EVRVQVWFQNRR 611

  Fly   604 MSFQQQAQAHQ------HQTVVFQQQQPHQ----------------------PAAINHQHMHH-- 638
            ..:::|.::..      |.|     |.||:                      |..::|....:
  Fly   612 AKWRRQEKSESLRLGLTHFT-----QLPHRLGCGASGLPVDPWLSPPLLSALPGFLSHPQTVYPS 671

  Fly   639 -------LGNGE-TYSALGLQMENCEGYNNFGAAGTGGGYYEAGQQPPIPATHG--HGHHPHHVQ 693
                   |..|. |.|:|. .|.:...:|.......|.|.:...|.||.|..||  |.|..|||
  Fly   672 YLTPPLSLAPGNLTMSSLA-AMGHHHAHNGPPPPHVGHGGHGQPQPPPPPPPHGVPHPHGSHHV- 734

  Fly   694 VPAQAHAPIHAHHNSAAIPGGVGVGPPPSHIHGFAINGGPAVQGQAFGNNGSTAAGTAAISGLEN 758
            ||....:|    |.|...|....:|.|  | ||....|.|......    .|:.|.|.|:|..::
  Fly   735 VPLSHLSP----HLSRMSPHATSLGSP--H-HGVTPLGTPLHSSLP----PSSTATTVAVSSSQS 788

  Fly   759 SNSS 762
            |:||
  Fly   789 SSSS 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	10/72 (14%)
Rx	NP_726006.3	Homeodomain	560..616	CDD:459649	10/63 (16%)
		OAR	876..892	CDD:461067