Protein Alignment pb and Hoxd12

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001178832.1
• Gene: Hoxd12 / 366082
• RGDID: 1309797
• Length: 268
• Species: Rattus norvegicus
• Alignment Length: 285
• Identity: 74/285 - (25%)
• Similarity: 102/285 - (35%)
• Gaps: 103/285 - (36%)

  Fly    14 GTQIKSESPLN-----------PLQVQTGQ--TSLPVGGCGGAGVVGGVGGVGVSVGQPGIGQQG 65
            |:|:.:..|::           |......|  |:...||.....:.|.        |..|:...|
  Rat    33 GSQLAALPPISYPRSALPWAATPASCTPAQPTTASAFGGFSQPYLTGS--------GPIGLQSPG 89

  Fly    66 VPPVPSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESPKI-----GTP- 124
            ....|.. .|...||       |.|   ||||.......|        .:|||..:     ||.
  Rat    90 TKDGPED-QVKFYTP-------DAA---TASEERSRTRPP--------FAPESSLVHSALKGTKY 135

  Fly   125 ----VGSGAIGGVGV----------------NVNVNVGVGVGYPVGVV----PQTPDGMDSVPEY 165
                ||..|.|.|.:                .:|:|:.|.|   .||.    ...|||:
  Rat   136 DFAGVGRAAPGSVTLLQGAPCASNFKEDTKGPLNLNMAVQV---AGVASCLRSSLPDGL------ 191

  Fly   166 PWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIE 230
            ||....                        |..|:.|..||..|:.|||.||..|:::.|.:|.|
  Rat   192 PWGAAP------------------------GRARKKRKPYTKQQIAELENEFLVNEFINRQKRKE 232

  Fly   231 IAASLDLTERQVKVWFQNRRMKHKR 255
            ::..|:|:::|||:||||||||.||
  Rat   233 LSNRLNLSDQQVKIWFQNRRMKKKR 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	27/55 (49%)
Hoxd12	NP_001178832.1	Homeodomain	201..257	CDD:459649	27/55 (49%)