Protein Alignment pb and otx5

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_851848.2
• Gene: otx5 / 353179
• ZFINID: ZDB-GENE-030508-1
• Length: 289
• Species: Danio rerio
• Alignment Length: 321
• Identity: 74/321 - (23%)
• Similarity: 103/321 - (32%)
• Gaps: 106/321 - (33%)

  Fly   147 YPVGVVPQTPDGMD---SVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNT 208
            |.|..:..|..|||   |...||     .|.||.                     ||.||.:|..
Zfish    10 YSVNGLTLTGTGMDLLHSAVGYP-----NTPRKQ---------------------RRERTTFTRA 48

  Fly   209 QLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGD 273
            ||..||..|...:|.....|.|:|..::|.|.:|:|||:|||.|.::|...:|
Zfish    49 QLDVLEALFSKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQT------------ 101

  Fly   274 DDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSNL 338
            ..|:......|||               |.:|..:.:.|||:.:.|.:....|..:..|..||
Zfish   102 SGQTKPRPPKKKS---------------SPARDSSASEPSASTSGPYSPPPPPPGTAITPSSS-- 149

  Fly   339 MGSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKDDGQVIKKEAVSTSSKASPFGYENST 403
                        ||..|:.|..|:                                ||.....|.
Zfish   150 ------------SATVSIWSPASI--------------------------------SPLPDPLSA 170

  Fly   404 PSLVSFRRDSDASAVGNAPT---SKAVGKKRFQSAANAIATPTPLSDSNSGNGSGGGPAGG 461
            ||....:|.|.......||.   |.|.....| :..:..:..:|:....|.:|....|..|
Zfish   171 PSTACLQRSSYPMTYSQAPAYGQSYAASSSYF-TGLDCSSYLSPMHPQLSASGGALSPMSG 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	24/55 (44%)
otx5	NP_851848.2	Homeodomain	39..94	CDD:459649	24/54 (44%)
		TF_Otx	157..231	CDD:427350	19/107 (18%)