Protein Alignment pb and tup

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_476775.1
• Gene: tup / 35147
• FlyBaseID: FBgn0003896
• Length: 534
• Species: Drosophila melanogaster
• Alignment Length: 382
• Identity: 77/382 - (20%)
• Similarity: 125/382 - (32%)
• Gaps: 164/382 - (42%)

  Fly   170 EKKTSRKSSNNNN---QGDNSITEF----------------------VPENGLPRRLRTAYTNTQ 209
            |...:..||||||   ..:|..:|.                      .|.:|.|.|:||.....|
  Fly   188 ESNNNISSSNNNNTNLSNNNHSSELGSMSDSGSESGSHKSIRDKRPSGPSDGKPTRVRTVLNEKQ 252

  Fly   210 LLELEKEFHFNKYLCRPRRI---EIAASLDLTERQVKVWFQNRRMKHKRQTLS-KTDDEDNKD-- 268
            |..|...::.|.   ||..:   ::.....|:.|.::|||||:|.|.|::|:. |...:..|:
  Fly   253 LHTLRTCYNANP---RPDALMKEQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQQEKEGR 314

  Fly   269 -----SLKGDD--DQSDSNSNSKKSCQGCELPSDDIP-----------DSTSNS----------- 304
                 :::|..  ..|....:|..:.||.::.:...|           |..||.
  Fly   315 KLGYGAMQGIPMIASSPVRHDSPLNLQGLDVQTYQPPWKALSDFALHADLDSNGAINTHTPAFQQ 379

  Fly   305 -----RGHNNN----TPSATNNNPSAG----------------NLTPN-----SSLETGISSNLM 339
                 .|::.|    .|...:::|:.|                |..||     |||::||:|:
  Fly   380 LVNQMHGYDLNGMPILPPHPHSHPAQGPPHQHPPPPGGPHNHQNQQPNQQPGGSSLDSGITSH-- 442

  Fly   340 GSTTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKDDGQVIKKEAVSTSSKASPFGYENSTP 404
                                                                      .:.:||.
  Fly   443 ----------------------------------------------------------HHPDSTD 449

  Fly   405 SLVSFRRDSDASAVGNAPTSKAVGKKRFQSAANAIATPTPLSDSNSGNGSGGGPAGG 461
            |.|::....|.|.:...|:|.:..     ||..:|::|.      ||.|:|||.|.|
  Fly   450 SYVTYLESDDKSKLALTPSSSSSA-----SAGTSISSPP------SGVGAGGGGAVG 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	18/58 (31%)
tup	NP_476775.1	LIM1_Isl	54..108	CDD:188752
		LIM2_Isl	116..171	CDD:188760
		HOX	241..297	CDD:197696	19/58 (33%)