Protein Alignment pb and HOXD9

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_055028.3
• Gene: HOXD9 / 3235
• HGNCID: 5140
• Length: 352
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 83/259 - (32%)
• Similarity: 110/259 - (42%)
• Gaps: 35/259 - (13%)

  Fly    28 VQTGQTSLPVGGCGGAGVVGGVGGVGVSVGQPGIGQQGVPPVPSVLMVNKMTPNCDKRSAD---T 89
            |::....|| |..||||..||.||     |.||.|....|..|:......:.|  :.|:|.   |
Human   116 VRSWMEPLP-GFPGGAGGGGGGGG-----GGPGRGPSPGPSGPANGRHYGIKP--ETRAAPAPAT 172

  Fly    90 AYWMTASEGGFINSQPSMAEFLNHLSPESPKIGTP----------VGSGAIGGVGVNVNVNVGVG 144
            |...|:|....::|.....|.  .::.||.....|          ..:.|.||.|....:....|
Human   173 AASTTSSSSTSLSSSSKRTEC--SVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATG 235

  Fly   145 VGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQ 209
            .|   |....:......:|.....:|:|...:........:|....::.... .|:.|..||..|
Human   236 TG---GSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARS-TRKKRCPYTKYQ 296

  Fly   210 LLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGD 273
            .|||||||.||.||.|.||.|:|..|:|||||||:||||||||.|:.:..|..        |||
Human   297 TLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCP--------KGD 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	37/55 (67%)
HOXD9	NP_055028.3	Hox9_act	11..>164	CDD:461369	19/55 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..208		26/90 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	229..276		7/49 (14%)
		Homeodomain	286..337	CDD:459649	33/50 (66%)