Protein Alignment pb and HOXD8

DIOPT Version :9

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_062458.1
• Gene: HOXD8 / 3234
• HGNCID: 5139
• Length: 290
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 84/275 - (30%)
• Similarity: 108/275 - (39%)
• Gaps: 84/275 - (30%)

  Fly    36 PVG-GCGGAGVVG----GVGGVGVSVGQPGIGQQGVPPVPSVLMVNKMTPNCDKRSADTAYWMTA 95
            |.| ||||....|    ..||     |.|....|..||.|.........|.|
Human    78 PSGTGCGGREGRGQEYFHPGG-----GSPAAAYQAAPPPPPHPPPPPPPPPC------------- 124

  Fly    96 SEGGF-INSQPSMAEFLNHLSPESPKIGTPVGSGAIGGVGVNVNVNVGVGVGYP-----VGVVPQ 154
              ||. .:.:|  |:|..:.:.:...|.|......:              |.||     .|.:.:
Human   125 --GGIACHGEP--AKFYGYDNLQRQPIFTTQQEAEL--------------VQYPDCKSSSGNIGE 171

  Fly   155 TPDGMD--SVPE--YPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEK 215
            .||.::  |.|.  :|||:.:....:                      ||.|..|:..|.|||||
Human   172 DPDHLNQSSSPSQMFPWMRPQAAPGR----------------------RRGRQTYSRFQTLELEK 214

  Fly   216 EFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSN 280
            ||.||.||.|.||||::.:|.|||||||:||||||||.|:        |:|||... ...|...:
Human   215 EFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKK--------ENNKDKFP-VSRQEVKD 270

  Fly   281 SNSKKSCQGCELPSD 295
            ..:||..|  ||..|
Human   271 GETKKEAQ--ELEED 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	COG5576	168..274	CDD:227863	43/105 (41%)
		Homeobox	202..254	CDD:278475	35/51 (69%)
HOXD8	NP_062458.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..127		18/68 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..200		9/60 (15%)
		Homeobox	201..253	CDD:278475	35/51 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..290		11/32 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810