Protein Alignment pb and HOXC11

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_055027.1
• Gene: HOXC11 / 3227
• HGNCID: 5123
• Length: 304
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 61/220 - (27%)
• Similarity: 92/220 - (41%)
• Gaps: 65/220 - (29%)

  Fly    66 VPP--VPSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESPKIGTPVGSG 128
            :||  |..:||.|:                 .|.||             |..|.:|. .||.|..
Human   105 LPPSTVTEILMKNE-----------------GSYGG-------------HHHPSAPH-ATPAGFY 138

  Fly   129 AIGGVGVNVNV-----------NVGVGVGYPVGVVPQTPDG-MDSVPEYPWMK----------EK 171
            :    .||.|.           |...|.|.|....|.:..| ....||.|...          |.
Human   139 S----SVNKNSVLPQAFDRFFDNAYCGGGDPPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEA 199

  Fly   172 KTSRKSSNNNNQGD-NSITEFVPENGLP-----RRLRTAYTNTQLLELEKEFHFNKYLCRPRRIE 230
            :...:::|.::.|. :|:.:...:...|     |:.|..|:..|:.|||:||.||.|:.:.:|::
Human   200 EAEEENTNPSSSGSAHSVAKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQ 264

  Fly   231 IAASLDLTERQVKVWFQNRRMKHKR 255
            ::..|:||:||||:||||||||.|:
Human   265 LSRMLNLTDRQVKIWFQNRRMKEKK 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	28/55 (51%)
HOXC11	NP_055027.1	DUF3528	42..161	CDD:432284	19/90 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..237		11/70 (16%)
		Homeodomain	233..289	CDD:459649	28/55 (51%)