Protein Alignment pb and HOXC9

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_008828.1
• Gene: HOXC9 / 3225
• HGNCID: 5130
• Length: 260
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 72/221 - (32%)
• Similarity: 95/221 - (42%)
• Gaps: 30/221 - (13%)

  Fly    58 QPGIGQQGVPPVP--SVLMVNKMTPNCDKRSADTAY---WMTASEGGFINSQPSMAEFLNH--LS 115
            :|.:......|||  |.::.:...|. ....|||.|   |:....|..  |.||......|  |.
Human    58 KPAVFSTSWAPVPSQSSVVYHPYGPQ-PHLGADTRYMRTWLEPLSGAV--SFPSFPAGGRHYALK 119

  Fly   116 PES-PKIGTPVGSGAIGGVGVNVNVNVGVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSN 179
            |:: |              |...:...|.|..||..:.....:..|..|:.....|......|.:
Human   120 PDAYP--------------GRRADCGPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKH 170

  Fly   180 NNNQGD----NSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTER 240
            ...:.|    |.:..::.... .|:.|..||..|.|||||||.||.||.|.||.|:|..|:||||
Human   171 KEEKADLDPSNPVANWIHARS-TRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTER 234

  Fly   241 QVKVWFQNRRMKHKRQTLSKTDDEDN 266
            |||:||||||||.|:....|||.|.:
Human   235 QVKIWFQNRRMKMKKMNKEKTDKEQS 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	37/55 (67%)
HOXC9	NP_008828.1	Hox9_act	1..179	CDD:461369	29/137 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..181		12/74 (16%)
		Homeodomain	193..241	CDD:459649	30/47 (64%)