DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pb and HOXC6

DIOPT Version :9

Sequence 1:	NP_476669.3	Gene:	pb / 40826	FlyBaseID:	FBgn0051481	Length:	782	Species:	Drosophila melanogaster
Sequence 2:	NP_004494.1	Gene:	HOXC6 / 3223	HGNCID:	5128	Length:	235	Species:	Homo sapiens

Alignment Length:	159	Identity:	62/159 - (38%)
Similarity:	81/159 - (50%)	Gaps:	23/159 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 VGVNVNVNVGVGVGYPVG-VVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENG 196
            :|.|...::........| ..||  |...|:..||||:..        |::.|       |....
Human    92 LGHNTQTSIAQDFSSEQGRTAPQ--DQKASIQIYPWMQRM--------NSHSG-------VGYGA 139

  Fly   197 LPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQ----- 256
            ..||.|..|:..|.||||||||||:||.|.||||||.:|.|||||:|:||||||||.|::
Human   140 DRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTS 204

  Fly   257 TLSKTDDEDNKDSLKGDDDQSDSNSNSKK 285
            |||........|||.|.:::.:.....|:
Human   205 TLSGGGGGATADSLGGKEEKREETEEEKQ 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	COG5576	168..274	CDD:227863	51/110 (46%)
pb	NP_476669.3	Homeobox	202..254	CDD:278475	37/51 (73%)
HOXC6	NP_004494.1	Antp-type hexapeptide	122..127		3/4 (75%)
		Homeobox	145..198	CDD:395001	37/52 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	200..235		8/34 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810