DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pb and HOXB8

DIOPT Version :9

Sequence 1:	NP_476669.3	Gene:	pb / 40826	FlyBaseID:	FBgn0051481	Length:	782	Species:	Drosophila melanogaster
Sequence 2:	NP_076921.1	Gene:	HOXB8 / 3218	HGNCID:	5119	Length:	243	Species:	Homo sapiens

Alignment Length:	151	Identity:	51/151 - (33%)
Similarity:	67/151 - (44%)	Gaps:	52/151 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   157 DGMDSVPE----YPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEF 217
            :|.:..|.    :|||:.:..:.:                      ||.|..|:..|.|||||||
Human   123 EGSEQSPSPTQLFPWMRPQAAAGR----------------------RRGRQTYSRYQTLELEKEF 165

  Fly   218 HFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDD-------- 274
            .||.||.|.||||::.:|.|||||||:||||||||.|:        |:|||......
Human   166 LFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKK--------ENNKDKFPSSKCEQEELEK 222

  Fly   275 ----------DQSDSNSNSKK 285
                      |:.|:....||
Human   223 QKLERAPEAADEGDAQKGDKK 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	COG5576	168..274	CDD:227863	43/105 (41%)
pb	NP_476669.3	Homeobox	202..254	CDD:278475	35/51 (69%)
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		2/4 (50%)
		Homeobox	150..203	CDD:395001	35/52 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	203..243		6/47 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810