Protein Alignment pb and HOXB7

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_004493.3
• Gene: HOXB7 / 3217
• HGNCID: 5118
• Length: 217
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 74/237 - (31%)
• Similarity: 97/237 - (40%)
• Gaps: 74/237 - (31%)

  Fly    84 KRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESPKIGTPVGSGAI----------GGVGVNVN 138
            |..|.::.:.|    |....|.|.|...|   |:.|..|  .||||.          ||.|:...
Human    13 KYPASSSVFAT----GAFPEQTSCAFASN---PQRPGYG--AGSGASFAASMQGLYPGGGGMAGQ 68

  Fly   139 VNVGV-GVGYPV-----------------GVVP---------QTPDGMDSVPE-----YPWMKEK 171
            ...|| ..||.:                 ||.|         :.....|...|     ||||:..
Human    69 SAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAESNFRIYPWMRSS 133

  Fly   172 KTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLD 236
            .|.||                       |.|..||..|.||||||||:|:||.|.||||||.:|.
Human   134 GTDRK-----------------------RGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLC 175

  Fly   237 LTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSD 278
            |||||:|:||||||||.|::..:.......:|..:.::::.:
Human   176 LTERQIKIWFQNRRMKWKKENKTAGPGTTGQDRAEAEEEEEE 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	38/55 (69%)
HOXB7	NP_004493.3	Antp-type hexapeptide	126..131		3/4 (75%)
		Homeodomain	138..194	CDD:459649	39/78 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..217		1/22 (5%)