DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment pb and HOXB6

DIOPT Version :9

Sequence 1:NP_476669.3 Gene:pb / 40826 FlyBaseID:FBgn0051481 Length:782 Species:Drosophila melanogaster
Sequence 2:XP_011523029.1 Gene:HOXB6 / 3216 HGNCID:5117 Length:288 Species:Homo sapiens


Alignment Length:253 Identity:78/253 - (30%)
Similarity:102/253 - (40%) Gaps:79/253 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    67 PPVP-SVLMVNKMTPNCDKRSADTAYWMTASEG--GFINSQP----SMAEFLNHL-SPESPKIGT 123
            ||:| |...||...|            :|.:.|  .|:...|    ..|:.|.|. :|..|..|.
Human    61 PPLPMSSYFVNSTFP------------VTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQ 113

  Fly   124 PVGSG-------AIGGVGVNVNVNVGVGVGY------------------------------PVGV 151
            ..|..       |.||.|.....:.|....:                              ...|
Human   114 DKGFATSSYYPPAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQDKSV 178

  Fly   152 VPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKE 216
            ..:|.:...|.|.||||:...:...||            |.|..   ||.|..||..|.||||||
Human   179 FGETEEQKCSTPVYPWMQRMNSCNSSS------------FGPSG---RRGRQTYTRYQTLELEKE 228

  Fly   217 FHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQT-------LSKTDDEDNK 267
            ||:|:||.|.||||||.:|.|||||:|:||||||||.|:::       ||..::|:.:
Human   229 FHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQ 286

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pbNP_476669.3 COG5576 168..274 CDD:227863 48/107 (45%)
Homeobox 202..254 CDD:278475 37/51 (73%)
HOXB6XP_011523029.1 Homeobox 214..266 CDD:278475 37/51 (73%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

Return to query results.
Submit another query.