Protein Alignment pb and HOXB4

DIOPT Version :9

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_076920.1
• Gene: HOXB4 / 3214
• HGNCID: 5115
• Length: 251
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 72/263 - (27%)
• Similarity: 98/263 - (37%)
• Gaps: 99/263 - (37%)

  Fly    59 PGIGQQGVPPVPSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESPKIGT 123
            ||:..:...|.|:..::.:....|:..|:..             ..|..|:...|.||.......
Human    87 PGLSPRAPAPPPAGALLPEPGQRCEAVSSSP-------------PPPPCAQNPLHPSPSHSACKE 138

  Fly   124 PVGSGAIGGVGVNVNVNVGVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSI 188
            ||                                      .||||::...|  :.|.|..|
Human   139 PV--------------------------------------VYPWMRKVHVS--TVNPNYAG---- 159

  Fly   189 TEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKH 253
                   |.|:|.|||||..|:||||||||:|:||.|.||:|||.:|.|:|||:|:||||||||.
Human   160 -------GEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKW 217

  Fly   254 KRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNN 318
            |:         |:|                        ||:..|  .:..:.|.....|...|..
Human   218 KK---------DHK------------------------LPNTKI--RSGGAAGSAGGPPGRPNGG 247

  Fly   319 PSA 321
            |.|
Human   248 PRA 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	COG5576	168..274	CDD:227863	48/105 (46%)
		Homeobox	202..254	CDD:278475	37/51 (73%)
HOXB4	NP_076920.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..134		11/59 (19%)
		Antp-type hexapeptide	141..146		3/4 (75%)
		Homeobox	165..218	CDD:278475	37/52 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	220..251		10/57 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810