Protein Alignment pb and HOXB2

DIOPT Version :9

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_002136.1
• Gene: HOXB2 / 3212
• HGNCID: 5113
• Length: 356
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 123/339 - (36%)
• Similarity: 156/339 - (46%)
• Gaps: 63/339 - (18%)

  Fly    97 EGGFINSQPSMAEFLNHLS-----------PESPKIGTP---------VGSGAIGGVGVNVNVNV 141
            |.||||||||:||.|....           .||..|..|         :..||............
Human     8 EIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPFEQTFPSLQPGASTLQRPRSQKRA 72

  Fly   142 GVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPEN---------GL 197
            ..|...|....|..| .....||:|||||||:::|.|.:.. ..:.....||.:         ||
Human    73 EDGPALPPPPPPPLP-AAPPAPEFPWMKEKKSAKKPSQSAT-SPSPAASAVPASGVGSPADGLGL 135

  Fly   198 P-------RRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKR 255
            |       ||||||||||||||||||||||||||||||:||||.|||||||||||||||||||||
Human   136 PEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 200

  Fly   256 QTLSKTDDEDNKDSLKGD-DDQSD----------SNSNSKKSCQGCELPSDDIPDSTS------- 302
            ||..: :..|.:.:..|. :|..|          ..|.|:.:.:.|..|.:.:|.:.|
Human   201 QTQHR-EPPDGEPACPGALEDICDPAEEPAASPGGPSASRAAWEACCHPPEVVPGALSADPRPLA 264

  Fly   303 -NSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSNLMGSTTVSASNVISADSSVASSVSLDEDI 366
             ...|...::|.....  .||.|.| ..|...:.|....|..:...|..:|||.:..|..|...:
Human   265 VRLEGAGASSPGCALR--GAGGLEP-GPLPEDVFSGRQDSPFLPDLNFFAADSCLQLSGGLSPSL 326

  Fly   367 EES--SPIKVKKKD 378
            :.|  ||:...:::
Human   327 QGSLDSPVPFSEEE 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	COG5576	168..274	CDD:227863	71/122 (58%)
		Homeobox	202..254	CDD:278475	49/51 (96%)
HOXB2	NP_002136.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..142		26/104 (25%)
		Antp-type hexapeptide	94..99		3/4 (75%)
		Homeobox	147..199	CDD:278475	49/51 (96%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..240		12/43 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158764
Domainoid	1	1.000	117	1.000	Domainoid score	I5916
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	1	1.000	-	-		otm40786
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR45664
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6877
SonicParanoid	1	1.000	-	-		X2356
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.830