Protein Alignment pb and HOXB2

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_002136.1
• Gene: HOXB2 / 3212
• HGNCID: 5113
• Length: 356
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 123/339 - (36%)
• Similarity: 156/339 - (46%)
• Gaps: 63/339 - (18%)

  Fly    97 EGGFINSQPSMAEFLNHLS-----------PESPKIGTP---------VGSGAIGGVGVNVNVNV 141
            |.||||||||:||.|....           .||..|..|         :..||............
Human     8 EIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPPPPPFEQTFPSLQPGASTLQRPRSQKRA 72

  Fly   142 GVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPEN---------GL 197
            ..|...|....|..| .....||:|||||||:::|.|.:.. ..:.....||.:         ||
Human    73 EDGPALPPPPPPPLP-AAPPAPEFPWMKEKKSAKKPSQSAT-SPSPAASAVPASGVGSPADGLGL 135

  Fly   198 P-------RRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKR 255
            |       ||||||||||||||||||||||||||||||:||||.|||||||||||||||||||||
Human   136 PEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 200

  Fly   256 QTLSKTDDEDNKDSLKGD-DDQSD----------SNSNSKKSCQGCELPSDDIPDSTS------- 302
            ||..: :..|.:.:..|. :|..|          ..|.|:.:.:.|..|.:.:|.:.|
Human   201 QTQHR-EPPDGEPACPGALEDICDPAEEPAASPGGPSASRAAWEACCHPPEVVPGALSADPRPLA 264

  Fly   303 -NSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSNLMGSTTVSASNVISADSSVASSVSLDEDI 366
             ...|...::|.....  .||.|.| ..|...:.|....|..:...|..:|||.:..|..|...:
Human   265 VRLEGAGASSPGCALR--GAGGLEP-GPLPEDVFSGRQDSPFLPDLNFFAADSCLQLSGGLSPSL 326

  Fly   367 EES--SPIKVKKKD 378
            :.|  ||:...:::
Human   327 QGSLDSPVPFSEEE 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	53/55 (96%)
HOXB2	NP_002136.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..142		26/104 (25%)
		Antp-type hexapeptide	94..99		3/4 (75%)
		Homeodomain	144..200	CDD:459649	53/55 (96%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..240		12/43 (28%)