Protein Alignment pb and HOXA10

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_061824.3
• Gene: HOXA10 / 3206
• HGNCID: 5100
• Length: 410
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 89/321 - (27%)
• Similarity: 114/321 - (35%)
• Gaps: 114/321 - (35%)

  Fly    32 QTSLPVGGCGGAGVVGGVGGVGVSV-----------------GQPGIGQQGVPPVP--------- 70
            :.:.|..|.||.|:..|..|.|.|.                 |.|...||..||.|
Human    90 EAASPGSGGGGGGLGPGAHGYGPSPIDLWLDAPRSCRMEPPDGPPPPPQQQPPPPPQPPQPAPQA 154

  Fly    71 ------------SVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESPKIGT 123
                        |...:......|.|.||      ||:|         :|.|.....|:...:||
Human   155 TSCSFAQNIKEESSYCLYDSADKCPKVSA------TAAE---------LAPFPRGPPPDGCALGT 204

  Fly   124 ----PV----------------GSGAIG----GVGVNVNVNVGVGVGYPVGVVPQTPD------G 158
                ||                |||..|    |.|.......|.|...|..:...:.|      .
Human   205 SSGVPVPGYFRLSQAYGTAKGYGSGGGGAQQLGAGPFPAQPPGRGFDLPPALASGSADAARKERA 269

  Fly   159 MDSVP-----------------------------EYPWMKEKKTSRKSSNNNNQGDNSITEFVPE 194
            :||.|                             ..|....|.:..|.|..|::|:|:......:
Human   270 LDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKDSLGNSKGENAANWLTAK 334

  Fly   195 NGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKR 255
            :|  |:.|..||..|.|||||||.||.||.|.||:||:.|:.||:||||:||||||||.|:
Human   335 SG--RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKK 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	36/55 (65%)
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..158		16/67 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..339		22/119 (18%)
		Homeodomain	337..393	CDD:459649	36/55 (65%)