Protein Alignment pb and MNX1

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_005506.3
• Gene: MNX1 / 3110
• HGNCID: 4979
• Length: 401
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 93/318 - (29%)
• Similarity: 128/318 - (40%)
• Gaps: 48/318 - (15%)

  Fly     6 SSLDTTSMGTQIKSESPLNPLQVQTGQTSLPVGGCGGAGVVGGVGGVGVSVGQPGIGQQGVPPVP 70
            ||....:...::::|||..|..:......||..|..|||  ||.||.|...|.|.
Human    62 SSEPPAAPADRLRAESPSPPRLLAAHCALLPKPGFLGAG--GGGGGTGGGHGGPH---------- 114

  Fly    71 SVLMVNKMTPNCDKRSADTAYWMTASEGGF-INSQPSMAEFLNHLSPESPKIGTPV-GSGAIGGV 133
                 :...|.....:|..|  ..|:.||. :...|..|:....|..::...|.|| |..|....
Human   115 -----HHAHPGAAAAAAAAA--AAAAAGGLALGLHPGGAQGGAGLPAQAALYGHPVYGYSAAAAA 172

  Fly   134 GVNVNVNVGVGVGYP--VGVVPQTPD-----GMDSVPEYPWMKEKKTSR---KSSNNNNQGDNSI 188
            ......:..:...||  .|..|..|.     |..:.....|::......   |..:.|:|..:::
Human   173 AALAGQHPALSYSYPQVQGAHPAHPADPIKLGAGTFQLDQWLRASTAGMILPKMPDFNSQAQSNL 237

  Fly   189 TEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKH 253
            .      |..||.|||:|:.||||||.:|..||||.||:|.|:|.||.|||.|||:||||||||.
Human   238 L------GKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKW 296

  Fly   254 KRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQ---GCELPSD--------DIPDS 300
            ||...:|.......:..||....:......:...:   |...|.|        |:.||
Human   297 KRSKKAKEQAAQEAEKQKGGGGGAGKGGAEEPGAEELLGPPAPGDKGSGRRLRDLRDS 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	38/55 (69%)
MNX1	NP_005506.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..78		3/15 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..120		7/33 (21%)
		Homeodomain	242..298	CDD:459649	38/55 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..401		9/56 (16%)