Protein Alignment pb and otx2b

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_571326.1
• Gene: otx2b / 30501
• ZFINID: ZDB-GENE-980526-406
• Length: 289
• Species: Danio rerio
• Alignment Length: 315
• Identity: 73/315 - (23%)
• Similarity: 115/315 - (36%)
• Gaps: 82/315 - (26%)

  Fly   147 YPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLL 211
            |.|..:..|..|||.:  :|.:....|.||.                     ||.||.:|..||.
Zfish    10 YTVNGLSLTTSGMDLL--HPSVGYPATPRKQ---------------------RRERTTFTRAQLD 51

  Fly   212 ELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQ 276
            .||..|...:|.....|.|:|..::|.|.:|:|||:|||.|.::|...:.:...||
Zfish    52 VLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNK--------- 107

  Fly   277 SDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSNLMGS 341
              .....|||....|                      |::.:.::|..||.|            |
Zfish   108 --VRPAKKKSSPARE----------------------ASSESGASGQFTPPS------------S 136

  Fly   342 TTVSASNVISADSSVASSVSLDEDIEESSPIKVKKKDDGQVIKKEAVSTSSKASPF--GYENSTP 404
            |:|.|.:..:|..|:.|..|:       ||:..........:::....|.::||.:  ||..||.
Zfish   137 TSVPAISTTTAPVSIWSPASI-------SPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTS 194

  Fly   405 SLVSFRRDSDASAVGNAPTSKAVGKKRFQSAANAIAT---PTPLSDSNSGNGSGG 456
            ........|..:.:.:..|..  |......::||:.:   .:|.|....|.|:.|
Zfish   195 YFGGMDCGSYLTPMHHQLTGP--GSTLSPMSSNAVTSHLNQSPASLPTQGYGASG 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	24/55 (44%)
otx2b	NP_571326.1	Homeodomain	39..94	CDD:459649	24/54 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..142		15/93 (16%)
		TF_Otx	153..234	CDD:427350	16/89 (18%)