Protein Alignment pb and otx2a

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: XP_073764513.1
• Gene: otx2a / 30462
• ZFINID: ZDB-GENE-980526-27
• Length: 364
• Species: Danio rerio
• Alignment Length: 519
• Identity: 116/519 - (22%)
• Similarity: 153/519 - (29%)
• Gaps: 214/519 - (41%)

  Fly   166 PW----MKEKKTSRKSSNNNNQGDNSITEFVPENGLP------RRLRTAYTNTQLLELEKEFHFN 220
            ||    |...|.:..:.|....|..::....|..|.|      ||.||.:|.|||..||..|...
Zfish    22 PWSSTMMSYLKQAPYAMNGLGLGGATMDLLHPSVGYPTNPRKQRRERTTFTRTQLDILESLFAKT 86

  Fly   221 KYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKK 285
            :|.....|.|:|..::|.|.:|:|||:|||.|.::|                   |..|::|||.
Zfish    87 RYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-------------------QQQSSTNSKI 132

  Fly   286 SCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSNLMGSTTVSASNVI 350
            .      |:...|..:..|.|           :.|:|:.||     ..:||:...|::.|.||
Zfish   133 R------PAKKKPSPSRESPG-----------SESSGHFTP-----PAVSSSSSSSSSSSGSN-- 173

  Fly   351 SADSSVASSVSLDEDIEESSPIKVKKKDDGQVIKKEAVSTSSKASPFGYENSTPSLVSFRRDSDA 415
               .|..|.|.|                         :|:||..:|      .||:.|....|..
Zfish   174 ---PSALSGVGL-------------------------ISSSSSGTP------VPSIWSPAPVSPV 204

  Fly   416 SAVGNAPTSKAVGKKRFQSAANAIATPTPLSDSNSGNGSGGGPAGGYFPGYYPSPKQQQQVQQQQ 480
            .|..:.|.               |:.|...|.......||||..|  .|. ||.|..|.
Zfish   205 PAPPSLPD---------------ISPPASASCMQRAMSSGGGTTG--VPS-YPMPYNQA------ 245

  Fly   481 LHPQQQQ-LPQQQPQDYYGKYDIEFAASPHHNPHNKQQALHGEYLSPKPSSANFHQNSQQQQQND 544
              |...| .|......|:|..|.                  |.||:|....|
Zfish   246 --PSYAQGYPTSNAASYFGGMDC------------------GSYLAPMTGHA------------- 277

  Fly   545 HFYYNYNDTNGTPYLNHQQQHHHHAQHHQQQQHHQNHVADFEGPVNGPSNFNNGAYYDNMSFQQQ 609
                                |||...||.|                             :|....
Zfish   278 --------------------HHHPHAHHSQ-----------------------------LSTAAA 293

  Fly   610 AQAHQHQTVVFQQQQPHQPAAINHQHMHHLGNGETYSALGLQMENCEGYN---------NFGAA 664
            ...|.|         ||.....:..|.||.|.|.|  ||.....:|..|.         ||.:|
Zfish   294 VSGHHH---------PHHIGQSSGHHPHHQGYGGT--ALPFSSSDCLDYKEQVASSWKLNFSSA 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	25/55 (45%)
otx2a	XP_073764513.1	None