DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pb and hoxb4a

DIOPT Version :9

Sequence 1:	NP_476669.3	Gene:	pb / 40826	FlyBaseID:	FBgn0051481	Length:	782	Species:	Drosophila melanogaster
Sequence 2:	NP_571193.1	Gene:	hoxb4a / 30340	ZFINID:	ZDB-GENE-990415-105	Length:	246	Species:	Danio rerio

Alignment Length:	178	Identity:	64/178 - (35%)
Similarity:	82/178 - (46%)	Gaps:	49/178 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 VVPQTPDGMDSVPE---------------YPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRR 200
            |.|..|......|.               |||||:...:..|.|.:             .|.|:|
Zfish   102 VTPSPPPACGQTPTSQNTSTVSSRKDPVVYPWMKKVHVNIVSPNYS-------------GGEPKR 153

  Fly   201 LRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDED 265
            .|||||..|:||||||||:|:||.|.||:|||.:|.|:|||:|:||||||||.|:         |
Zfish   154 SRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHTLCLSERQIKIWFQNRRMKWKK---------D 209

  Fly   266 NKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNNTPS 313
            :|  |.....:|:|.|.:...|          |...||....:...||
Zfish   210 HK--LPNTKIRSNSASTNSSGC----------PTLCSNQSRASGPPPS 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	COG5576	168..274	CDD:227863	48/105 (46%)
pb	NP_476669.3	Homeobox	202..254	CDD:278475	37/51 (73%)
hoxb4a	NP_571193.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..125		4/22 (18%)
		Antp-type hexapeptide	130..135		3/4 (75%)
		Homeobox	154..207	CDD:278475	37/52 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	210..246		11/48 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810