Protein Alignment pb and Hoxc12

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001100266.1
• Gene: Hoxc12 / 300262
• RGDID: 1310539
• Length: 280
• Species: Rattus norvegicus
• Alignment Length: 263
• Identity: 69/263 - (26%)
• Similarity: 97/263 - (36%)
• Gaps: 56/263 - (21%)

  Fly     3 EVCSSLDTTSMGTQIKSESP------LNPLQVQTGQTSLPVGGCGGAGVVGGVGGVGVSVGQPGI 61
            |.|:......:|:.:....|      |..::...|....|....||.|:.....|     .:||.
  Rat    59 EPCNGYPQPYLGSPVSLNPPFGRTCELARVEDSKGYYREPCAEGGGGGLKREERG-----REPGA 118

  Fly    62 GQQGVPPVPSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESPKIGTPVG 126
            |     |..::|.:....|.......|   :.....||..|:.|.      |..|....:.:...
  Rat   119 G-----PGAALLQLEPSGPPALGFKYD---YPAGGGGGDGNTGPP------HDPPSCQSLESDSS 169

  Fly   127 SGAIGGVGVNVNVNVGVGVGYPVGVV-PQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITE 190
            |..:.      ..|.|...|.|..:| |..|.|..|....||......|||.
  Rat   170 SSLLN------EGNKGASAGDPGSLVSPLNPGGGLSASGAPWYPIHSRSRKK------------- 215

  Fly   191 FVPENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKR 255
                       |..|:..||.|||.||..|:::.|.||.|::..|:|:::|||:||||||||.||
  Rat   216 -----------RKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKR 269

  Fly   256 QTL 258
            ..|
  Rat   270 LLL 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	27/55 (49%)
Hoxc12	NP_001100266.1	Homeodomain	213..269	CDD:459649	29/79 (37%)