Protein Alignment pb and Nkx1-1

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: XP_234082.6
• Gene: Nkx1-1 / 298981
• RGDID: 1564874
• Length: 443
• Species: Rattus norvegicus
• Alignment Length: 334
• Identity: 92/334 - (27%)
• Similarity: 116/334 - (34%)
• Gaps: 113/334 - (33%)

  Fly    27 QVQTGQ-TSLPVGGCGGAGVVGGVGGVGVSVGQPGIGQQGVPPVPSVLMVNKMTPNCDKRSADTA 90
            :||..| |..|.||.||.|..|.        |..|..:....||                  |.|
  Rat   201 EVQDVQGTEEPRGGSGGLGARGS--------GCSGAAEVEASPV------------------DEA 239

  Fly    91 YWMTASEGGFINSQPSMAEFLNHLSPESPKIGTPVGSGAIGGVGVNVNVNVGVGVGYPVGVVPQT 155
                |:.|...|            ||.:|  |.||.:...|..|                   .|
  Rat   240 ----AAPGPRGN------------SPGAP--GPPVTAAGAGNAG-------------------ST 267

  Fly   156 PDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFN 220
            |.|. :|...|  |.|:|...|                ::|.|||.|||:|..||:.||.:|...
  Rat   268 PQGA-AVATKP--KRKRTGSDS----------------KSGKPRRARTAFTYEQLVALENKFKAT 313

  Fly   221 KYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSN--- 282
            :||....|:.:|.||.|||.|||:||||||.|.|:|.             .|.|..:.:...
  Rat   314 RYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQN-------------PGADTSAPTGGGGGP 365

  Fly   283 SKKSCQGCELPSDDIPDSTSNSRGHNNNTPSATNNNP-----SAGNLT-----PNSSLETGISSN 337
            ...:..|..||....|.|.|...|    .|.|.:...     |.|.|.     |..|....:|..
  Rat   366 GPGAGPGAGLPGGLSPLSPSPPMG----APLALHGPAGYPAHSPGGLVCAAQLPFLSSPAVLSPF 426

  Fly   338 LMGSTTVSA 346
            ::||.|..|
  Rat   427 VLGSQTYGA 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	30/55 (55%)
Nkx1-1	XP_234082.6	Homeodomain	292..348	CDD:459649	30/55 (55%)