Protein Alignment pb and tlx3b

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_739572.2
• Gene: tlx3b / 266965
• ZFINID: ZDB-GENE-021021-1
• Length: 300
• Species: Danio rerio
• Alignment Length: 285
• Identity: 67/285 - (23%)
• Similarity: 116/285 - (40%)
• Gaps: 69/285 - (24%)

  Fly    81 NCDKRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESPKIGTPVG---------SGAIGGV--- 133
            |..:.|::::...:::.||..:                  :|:|.|         :|...|:
Zfish    42 NSTRNSSESSSGSSSASGGCYH------------------LGSPTGASATPYTTLTGTFHGIAAP 88

  Fly   134 -------GVNVNVNVGVGVGYP-----VGVVPQTPDGMDSVP-----EYPWMKEKKTSRKSSNNN 181
                   |:|:.:..|..:..|     ...||  |....:||     .:|||:..:...|
Zfish    89 YEESSPYGMNLTLAPGGVIRVPAHRPLAAAVP--PPMASAVPGLGSLSFPWMESSQRFAK----- 146

  Fly   182 NQGDNSITEFVP--------ENGLP---RRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASL 235
            ::...::|.|..        :|..|   ::.||:::..|:.||||.||..|||....|..:|.:|
Zfish   147 DRFAAALTPFTVARRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKTL 211

  Fly   236 DLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDS 300
            .:|:.|||.||||||.|.:|||..:.:.|..:.:......|.|:...|...    .:|:|.:...
Zfish   212 KMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRLMIQLQHDAFQKSLTD----SVPTDPLCIH 272

  Fly   301 TSNSRGHNNNTPSATNNNPSAGNLT 325
            .|:.....|..|.|:..:...|.:|
Zfish   273 NSSLFALQNLQPWASEESSKLGGVT 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	26/55 (47%)
tlx3b	NP_739572.2	Homeodomain	175..231	CDD:459649	26/55 (47%)