Protein Alignment pb and phx1

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_593776.1
• Gene: phx1 / 2542405
• PomBaseID: SPAC32A11.03C
• Length: 942
• Species: Schizosaccharomyces pombe
• Alignment Length: 918
• Identity: 174/918 - (18%)
• Similarity: 286/918 - (31%)
• Gaps: 323/918 - (35%)

  Fly    98 GGFINSQPSMAEFLNHLSPESPKIGTPVGSGAIGGVGVNVNVNVGVGVGYPVGVVPQTPDGMDSV 162
            ||.||...:.:|....:.||:..:........:|....:.|:.:      |.....|...|....
pombe    10 GGQINDNINYSEKRPTMLPENLSLSNYDMDSFLGQFPSDNNMQL------PHSTYEQHLQGEQQN 68

  Fly   163 PEYP-------------WMKEK-KTSRKSSNNNNQGD---------------------------- 185
            |..|             |.:|| |....|..:||..|
pombe    69 PTNPNYFPPEFDENKVDWKQEKPKPDAPSFADNNSFDNVNSSKLTNPSPVQPNIVKSESEPANSK 133

  Fly   186 -NSITEF---------------VPENG----LPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIE 230
             |.:.|.               .||:|    .|:..:...|..||..|.:||..:.......|.:
pombe   134 QNEVVEATSVEKAKENVAHESGTPESGGSTSAPKSKKQRLTADQLAYLLREFSKDTNPPPAIREK 198

  Fly   231 IAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSD 295
            |...|::.||.|.:||||||.|.|  .:|:..:|:.:..|:   :|.:.:|.::|
pombe   199 IGRELNIPERSVTIWFQNRRAKSK--LISRRQEEERQRILR---EQRELDSLNQK---------- 248

  Fly   296 DIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSNLMGSTTVSASNVISADSSVASSV 360
                 .|.:..|...:.|.|  :|..|.:..|..    .::.|:...|....|.......:.|
pombe   249 -----VSQAFAHEVLSTSPT--SPYVGGIAANRQ----YANTLLPKPTRKTGNFYMKSGPMQS-- 300

  Fly   361 SLDEDIEESS-PIKVKKKDDGQVIKKEAVSTS--SKASPFGYENSTPSLVSFRRDSDASAVGNAP 422
            |::..|.||. ||            ::::|::  :..||    |:.|  ||.:|...||:....|
pombe   301 SMEPCIAESDIPI------------RQSLSSTYYNSLSP----NAVP--VSSQRKYSASSYSAIP 347

  Fly   423 TSKAVGKKRF--QSAANAIAT-------PTPLSDSNS-----GNGSGG---------------GP 458
            .:.:|..:.|  :|..::.||       |.|.||..|     ...|||               ||
pombe   348 NAMSVSNQAFDVESPPSSYATPLTGIRMPQPESDLYSYPREVSPSSGGYRMFGHSKPSSYKASGP 412

  Fly   459 ------AGG----------------YFP--------------------GYYPSPK-------QQQ 474
                  |.|                ||.                    .:|..||       |.|
pombe   413 VRPPNMATGHMRTSSEPTSYDSEFYYFSCTLLVIGLWKRLRASPQDLMCFYSPPKKLFAYLIQFQ 477

  Fly   475 QVQQ---------QQLHPQQQQLP-------------QQQPQDYYGKYDIEFAASP-HHNPHNKQ 516
            .:|.         :.:|..:.:.|             :..|.:|:.:.||:.:..| .|...::.
pombe   478 GIQYRIEYSFFVIESIHVFRVEEPLLNELSATASSRDKPAPNEYWLQMDIQLSVPPVFHMITSEG 542

  Fly   517 QA---------------LHG---------------EYLSPKPSSA-------NFHQ------NSQ 538
            |.               ||.               ...||:..|.       |.||      .:|
pombe   543 QGNCTDFTEGNQASEVLLHSLMGRATSMFQMLDRVRRASPELGSVIRLQKGLNPHQFLDPQWANQ 607

  Fly   539 QQQQNDHFYYNYNDTN----------GTPYLNHQQQHHHHAQHHQQQQHHQNHVADFEGPVNGPS 593
            ..:|.|...:::...|          .:.|.|..|.....:.....:|....|:.        |.
pombe   608 LPRQPDSSVFDHQGRNPPIQGLSHDTSSEYGNKSQFKRLRSTSTPARQDLAQHLL--------PP 664

  Fly   594 NFNNGAYYDNMSFQQQAQAHQHQTVV---FQQQQPHQPAAINHQHMHHLGNGETYSALGLQMENC 655
            ..|........|.....||.:...|:   ..:...::| :::..:.||        .|.|.::|.
pombe   665 KTNTEGLMHAQSVSPITQAMKSANVLEGSSTRLNSYEP-SVSSAYPHH--------NLALNLDNT 720

  Fly   656 EGYNNFGAAGTGGGYYEAGQQPPIPATHGHGHHPHHVQVPAQAHAPIHAHHN-----------SA 709
            :    ||..||....|      |:.|....|..|.....|::   |: .|.|           :|
pombe   721 Q----FGELGTSNISY------PLSAPSDVGSLPRASNSPSR---PV-MHPNTQGINTEIKDMAA 771

  Fly   710 AIPGGVGVGPPPSHIHGFAINGGPAV----QGQAFGNNGSTAAGTAAISGLENSNSSDFNFLSNL 770
            ..|.....|..|   :.:::|...:|    |.:.||..||::..|...:..:..:...|..:|..
pombe   772 QFPNSQTGGLTP---NSWSMNTNVSVPFTTQNREFGGIGSSSISTTMNAPSQQLSQVPFGDVSLA 833

  Fly   771 ANDFAPEY 778
            ..:..|.|
pombe   834 TENSVPSY 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	19/55 (35%)
phx1	NP_593776.1	COG5576	116..272	CDD:227863	38/177 (21%)