Protein Alignment pb and Gbx1

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_001258382.1
• Gene: Gbx1 / 246149
• RGDID: 621864
• Length: 425
• Species: Rattus norvegicus
• Alignment Length: 292
• Identity: 83/292 - (28%)
• Similarity: 105/292 - (35%)
• Gaps: 100/292 - (34%)

  Fly    22 PLNPLQVQTGQTSLPVGGCGGAG-VVGGVGGVGV---SVGQPGIGQQGVPPVPSVL------MVN 76
            ||.||....|:.|...  |.|.| .|..:..:..   |..:|.....|.|.:.:..      .|:
  Rat   131 PLAPLASFAGRLSNTF--CAGLGQAVPSMVALTTALPSFAEPPDAYYGPPELAAAAAAAAASTVS 193

  Fly    77 KMTPNCDKRSADTAYWMTASE-------------------GGFINSQPSM-AEFLNHLSPE---S 118
            :..|....|..|.|  :.|.|                   ..|..:.||: ||...:.|.|   .
  Rat   194 RSNPEPPARRTDGA--LDADELLPAREKVTEPPPPPPPPPPHFSETFPSLPAEGKVYSSDEEKLE 256

  Fly   119 PKIGTPVGS-----------------------GAIGGVGVNVNVNVGVGV--GYPVGVVPQTPDG 158
            |..|.|.||                       ||:.|....:..::|.|.  |.||.....||.|
  Rat   257 PPAGEPAGSEPEEEGSGGDSEDSFLDSSAGGPGALLGPKPKLKGSLGTGAEEGTPVATGVTTPGG 321

  Fly   159 MDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKEFHFNKYL 223
                             ||                     ||.|||:|:.||||||||||..|||
  Rat   322 -----------------KS---------------------RRRRTAFTSEQLLELEKEFHCKKYL 348

  Fly   224 CRPRRIEIAASLDLTERQVKVWFQNRRMKHKR 255
            ....|.:||.:|.|:|.|||:||||||.|.||
  Rat   349 SLTERSQIAHALKLSEVQVKIWFQNRRAKWKR 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	35/55 (64%)
Gbx1	NP_001258382.1	Homeodomain	324..380	CDD:459649	35/55 (64%)