DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pb and Hoxc8

DIOPT Version :9

Sequence 1:	NP_476669.3	Gene:	pb / 40826	FlyBaseID:	FBgn0051481	Length:	782	Species:	Drosophila melanogaster
Sequence 2:	NP_001170797.2	Gene:	Hoxc8 / 24460	RGDID:	2821	Length:	242	Species:	Rattus norvegicus

Alignment Length:	224	Identity:	72/224 - (32%)
Similarity:	98/224 - (43%)	Gaps:	40/224 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 PNCDKRSADTAYWMTASEGGFINSQPSMAEFLNHLSPESPKIGTPVGSGAIGGVGVNVNV----- 139
            |....||....|....|..||.::...:.:|.:|            |:..|...|...|.
  Rat    29 PQSVGRSHALVYGPGGSAPGFQHASHHVQDFFHH------------GTSGISNSGYQQNPCSLSC 81

  Fly   140 --NVGVGVGYPVGVVP-QTPDGMD---SVPEYPWMKEKKTSRKSSNNNNQGDNSITEFV-----P 193
              :.....||.  .:| |:..|..   ||.:||..|....:..|....:...||....:     |
  Rat    82 HGDASKFYGYE--ALPRQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRP 144

  Fly   194 ENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTL 258
            .....|..|..|:..|.|||||||.||.||.|.||||::.:|.|||||||:||||||||.|:
  Rat   145 HAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKK--- 206

  Fly   259 SKTDDEDNKDSLKG--DDDQSDSNSNSKK 285
                 |:|||.|.|  |:::.:...|.::
  Rat   207 -----ENNKDKLPGARDEEKVEEEGNEEE 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	COG5576	168..274	CDD:227863	48/112 (43%)
pb	NP_476669.3	Homeobox	202..254	CDD:278475	35/51 (69%)
Hoxc8	NP_001170797.2	Homeobox	153..206	CDD:395001	35/52 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900