Protein Alignment pb and Gbx1

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_056554.1
• Gene: Gbx1 / 231044
• MGIID: 95667
• Length: 418
• Species: Mus musculus
• Alignment Length: 380
• Identity: 91/380 - (23%)
• Similarity: 115/380 - (30%)
• Gaps: 181/380 - (47%)

  Fly    13 MGTQIKSESPLNPLQVQTGQTSLPVGGCGGAGVVGGVGGVGVSVGQPG--------IG------- 62
            :|.:.:||..::....:.|..|......||    |..||.|.|.|.||        ||
Mouse    38 LGPRARSEPCVSARGARRGPGSAMQRAAGG----GAPGGSGGSSGGPGAAFSIDSLIGPPPPRSG 98

  Fly    63 ---------------------------QQGVPP----------------------VPSVLMVNKM 78
                                       ..|:||                      |||::.:...
Mouse    99 HLLYTGYPMFMPYRPLVLPQALAPAPLPAGLPPLAPLASFAGRLSNTFCAGLGQAVPSMVALTTA 163

  Fly    79 TPNCDKRSADTAYW----------MTASEGG---------------------------------- 99
            .|:.  .....||:          .|||...
Mouse   164 LPSF--AEPPDAYYGPPELAAAAASTASRSNPEPAARRTDGALDAEELLPAREKVTEPPPPPPPH 226

  Fly   100 FINSQPSM-AEFLNHLSPE---SPKIGTPVGS-----------------------GAIGGVGVNV 137
            |..:.||: ||...:.|.|   .|..|.|.||                       ||:.|....:
Mouse   227 FSETFPSLPAEGKVYSSDEEKLEPPAGDPAGSEQEEEGSGGDSEDSFLDSSAGGPGALLGPKPKL 291

  Fly   138 NVNVGVGV--GYPVGVVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRR 200
            ..:.|.|.  |.||.....||.|                 ||                     ||
Mouse   292 KGSPGTGAEEGTPVATGVTTPGG-----------------KS---------------------RR 318

  Fly   201 LRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKR 255
            .|||:|:.||||||||||..|||....|.:||.:|.|:|.|||:||||||.|.||
Mouse   319 RRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	35/55 (64%)
Gbx1	NP_056554.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..90		15/55 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..320		27/143 (19%)
		Homeodomain	317..373	CDD:459649	35/55 (64%)