Protein Alignment pb and EMX1

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 81/303 - (26%)
• Similarity: 114/303 - (37%)
• Gaps: 106/303 - (34%)

  Fly    41 GGAGVVGGVGGVGVSVGQPGIGQQGVPPVPSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQP 105
            ||.|  ||.||.|.............|..|:.|  |...|             :|:|..|::..|
Human    53 GGTG--GGTGGGGAGSHLLAAAASEEPLRPTAL--NYPHP-------------SAAEAAFVSGFP 100

  Fly   106 SMA-----------------EFLNHLSPESPKIGTPVGSGAIGGVGVNVNVNVGVGVGYPVGVVP 153
            :.|                 |.:||.:                         :.|...:.:|..|
Human   101 AAAAAGAGRSLYGGPELVFPEAMNHPA-------------------------LTVHPAHQLGASP 140

  Fly   154 QTP-------DGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGL---------PRRLR 202
            ..|       ...|.:..|||:         ..|...|.......||::||         |:|:|
Human   141 LQPPHSFFGAQHRDPLHFYPWV---------LRNRFFGHRFQASDVPQDGLLLHGPFARKPKRIR 196

  Fly   203 TAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNK 267
            ||::.:|||.||:.|..|.|:....|.::|.||.|:|.||||||||||.|:|||.|    :|:..
Human   197 TAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKL----EEEGP 257

  Fly   268 DSLKGDDDQSDSNSN-------SKKSCQGCELPSDDIPDSTSN 303
            :|     :|....|:       :.|...|     :|| |.|||
Human   258 ES-----EQKKKGSHHINRWRIATKQANG-----EDI-DVTSN 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	29/55 (53%)
EMX1	NP_004088.2	Homeodomain	193..249	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..290		15/56 (27%)