Protein Alignment pb and GSX2

DIOPT Version :9

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_573574.2
• Gene: GSX2 / 170825
• HGNCID: 24959
• Length: 304
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 79/288 - (27%)
• Similarity: 110/288 - (38%)
• Gaps: 111/288 - (38%)

  Fly    39 GCGGAGV-VGGVGGVGVSVGQPGIGQQGVPPVPSVLMVNKMTPNCDKRSADTAYWMTASEGGFIN 102
            |.||||. |.|.||.||:      |..|..|:..                           |..:
Human    79 GSGGAGAGVTGAGGSGVA------GAAGALPLLK---------------------------GQFS 110

  Fly   103 SQPSMAEFL-----------------NHLSPESPKIGTPVGSGAIGGVGVNVNVNVGVGVGYPVG 150
            |.|..|:|.                 :|..|:.|  |:...:.|......     ....:|:|..
Human   111 SAPGDAQFCPRVNHAHHHHHPPQHHHHHHQPQQP--GSAAAAAAAAAAAA-----AAAALGHPQH 168

  Fly   151 VVPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGD----------NSITEFVPENGLPRRLRTAY 205
            ..|..                     ::...|..|          .|....|| ||  :|:|||:
Human   169 HAPVC---------------------TATTYNVADPRRFHCLTMGGSDASQVP-NG--KRMRTAF 209

  Fly   206 TNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQ-------------- 256
            |:|||||||:||..|.||.|.||||||..|:|:|:|||:||||||:|||::
Human   210 TSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGTQRNSHAGCKC 274

  Fly   257 -----TLSKTDDEDNKDSLKGDDDQSDS 279
                 ..::::|||:......:||:..|
Human   275 VGSQVHYARSEDEDSLSPASANDDKEIS 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	COG5576	168..274	CDD:227863	49/134 (37%)
		Homeobox	202..254	CDD:278475	36/51 (71%)
GSX2	NP_573574.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..151		6/36 (17%)
		Homeobox	206..258	CDD:306543	36/51 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..304		6/20 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810