Protein Alignment pb and NKX2-3

DIOPT Version :10

• Sequence 1: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Sequence 2: NP_660328.2
• Gene: NKX2-3 / 159296
• HGNCID: 7836
• Length: 364
• Species: Homo sapiens
• Alignment Length: 129
• Identity: 42/129 - (32%)
• Similarity: 60/129 - (46%)
• Gaps: 20/129 - (15%)

  Fly   150 GVVPQ------------TPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLP---- 198
            |:.||            .|...:..||....:.:|:.:...:....||....|   |:..|
Human    86 GLCPQGYVHTVLRDSCSEPKEHEEEPEVVRDRSQKSCQLKKSLETAGDCKAAE---ESERPKPRS 147

  Fly   199 -RRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKT 261
             |:.|..::..|:.|||:.|...:||..|.|..:|:||.||..|||:||||||.|.|||...|:
Human   148 RRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKS 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	26/55 (47%)
NKX2-3	NP_660328.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..153		6/23 (26%)
		Homeodomain	149..205	CDD:459649	26/55 (47%)